Identification and treatment of latent tuberculosis infection (LTBI) can substantially reduce
the risk of developing active disease. However, there is no diagnostic gold standard for LTBI …

Despite achieving great public health strides to control tuberculosis (TB) within the United
States, it remains an enormous public health issue worldwide. Accurate statistics on …

Background Improved diagnostic tests for tuberculosis in children are needed. We
hypothesized that transcriptional signatures of host blood could be used to distinguish …

There is a critical need for improved diagnosis of tuberculosis in children, particularly in
young children with intrathoracic disease as this represents the most common type of …

Tuberculosis (TB) remains an important problem among children in the United States and
throughout the world. There is no diagnostic reference standard for latent tuberculosis …

Tuberculosis (TB) remains an important problem among children in the United States and
throughout the world. Although diagnosis and treatment of infection with Mycobacterium …

Identifying latently infected individuals is crucial for the elimination of tuberculosis (TB). We
evaluated for the first time the performance of a new type of interferon-γ release assay …

Many species within the genus Mycobacterium are prominent pathogens, above all
members of the M. tuberculosis complex, M. leprae, and M. ulcerans. In addition, there are …

Background Timely and accurate identification of people with latent tuberculosis infection
(LTBI) is important for controlling Mycobacterium tuberculosis (TB). There is no gold …

Latent infection with Mycobacterium tuberculosis (LTBI) is defined by the presence of M.
tuberculosis-specific immunity in the absence of active tuberculosis. LTBI is detected using …