Lung aeration, ventilation, and perfusion imaging

L Ball, G Scaramuzzo, J Herrmann… - Current opinion in …, 2022 - journals.lww.com
Lung aeration, ventilation, and perfusion imaging : Current Opinion in Critical Care Lung
aeration, ventilation, and perfusion imaging : Current Opinion in Critical Care Log in or Register …

Simulation-based optimisation to quantify heterogeneity of specific ventilation and perfusion in the lung by the inspired sinewave test

MC Tran, V Nguyen, R Bruce, DC Crockett… - Scientific reports, 2021 - nature.com
The degree of specific ventilatory heterogeneity (spatial unevenness of ventilation) of the
lung is a useful marker of early structural lung changes which has the potential to detect …

Intra-tidal PaO2 oscillations associated with mechanical ventilation: a pilot study to identify discrete morphologies in a porcine model

JN Cronin, DC Crockett, G Perchiazzi… - Intensive Care Medicine …, 2023 - Springer
Background Within-breath oscillations in arterial oxygen tension (PaO2) can be detected
using fast responding intra-arterial oxygen sensors in animal models. These PaO2 signals …

Real-time effects of PEEP and tidal volume on regional ventilation and perfusion in experimental lung injury

JB Borges, JN Cronin, DC Crockett… - Intensive care medicine …, 2020 - Springer
Background Real-time bedside information on regional ventilation and perfusion during
mechanical ventilation (MV) may help to elucidate the physiological and pathophysiological …

Bedside monitoring of lung volume available for gas exchange

MC Tran, DC Crockett, JN Cronin, JB Borges… - Intensive Care Medicine …, 2021 - Springer
Background Bedside measurement of lung volume may provide guidance in the
personalised setting of respiratory support, especially in patients with the acute respiratory …

[HTML][HTML] A novel tree shrew model of lipopolysaccharide-induced acute respiratory distress syndrome

J He, Y Zhao, Z Fu, L Chen, K Hu, X Lin, N Wang… - Journal of Advanced …, 2024 - Elsevier
Introduction Acute respiratory distress syndrome (ARDS) is a leading cause of respiratory
failure, with substantial attributable morbidity and mortality. The small animal models that are …

Validating the inspired sinewave technique to measure lung heterogeneity compared to atelectasis & over-distended volume in computed tomography images

MC Tran, PA Phan, DC Crockett… - ICASSP 2021-2021 …, 2021 - ieeexplore.ieee.org
The inspired sinewave technique (IST) is a non-invasive nonionising method which can
measure accurately lung parameters. Six anaesthetised pigs were studied after surfactant …

[PDF][PDF] Intra-tidal PaO

JN Cronin, DC Crockett, G Perchiazzi… - 2023 - icm-experimental.springeropen.com
Background Within-breath oscillations in arterial oxygen tension (PaO2) can be detected
using fast responding intra-arterial oxygen sensors in animal models. These PaO2 signals …

Lung measurement and quantification of lung heterogeneity using the Inspired Sinewave Test

MC Tran - 2021 - ora.ox.ac.uk
The lung is a complex organ. The most familiar and significant lung disease, chronic
obstructive pulmonary disease (COPD), can be severely debilitating. Additionally, acute lung …

Novel techniques to study cardiopulmonary physiology in a preclinical, saline-lavage model of the acute respiratory distress syndrome

D Crockett - 2019 - ora.ox.ac.uk
The acute respiratory distress syndrome (ARDS) affects 24.4% of all patients requiring
mechanical ventilation and has an associated mortality of up to 46%. The complex …