Neuroimaging studies have provided valuable insights into the macroscale impacts of
antidepressants on brain functions in patients with major depressive disorder. However, the …

Major depression affects millions of adults in the United States, and women are affected at
twice the rate of men. Approximately 30% of individuals may continue to experience …

Background: Depression causes emotional and physical disturbances which impacts
biological functions such as sleep, appetite, libido, and disinterest in sexual function. Since …

Placebo was conceived as an epistemological tool to control for incidental factors that could
influence investigated outcomes (1, 2). As a phenomenon, placebo has been …

This text provides a comprehensive and evidence-based introduction to psychiatric mental
health assessment and diagnosis in advanced nursing practice. Taking a clinical, case …

Background Since insomnia and depression are interrelated, improved sleep early in
antidepressant pharmacotherapy may predict a positive treatment outcome. We investigated …

ABSTRACT Introduction Major Depressive Disorder (MDD) is a chronic, relapsing, and
remitting disorder affecting over 250 million persons each year worldwide. More than 50% of …

Depression is a public health issue that needs to be addressed urgently in modern society,
and prevention is one of the most effective ways to tackle this problem. The key to effective …

Akin to a William Morris tapestry, Dr Stephen Rosenman explicates the ACE (activity,
cognition and emotion) Model described in the recent mood disorder clinical practice …

Abstract Late-life depression (LLD), diagnosed as major depressive disorder in older adults
(≥ 60 years), is a heterogeneous disorder characterized by a unique constellation of clinical …