Role of the gut–brain axis in energy and glucose metabolism

HR Wachsmuth, SN Weninger, FA Duca - Experimental & molecular …, 2022 - nature.com
The gastrointestinal tract plays a role in the development and treatment of metabolic
diseases. During a meal, the gut provides crucial information to the brain regarding …

Current directions in the auricular vagus nerve stimulation I–a physiological perspective

E Kaniusas, S Kampusch, M Tittgemeyer… - Frontiers in …, 2019 - frontiersin.org
Electrical stimulation of the auricular vagus nerve (aVNS) is an emerging technology in the
field of bioelectronic medicine with applications in therapy. Modulation of the afferent vagus …

[HTML][HTML] A neural circuit for gut-induced reward

W Han, LA Tellez, MH Perkins, IO Perez, T Qu… - Cell, 2018 - cell.com
The gut is now recognized as a major regulator of motivational and emotional states.
However, the relevant gut-brain neuronal circuitry remains unknown. We show that optical …

Rethinking food reward

IE de Araujo, M Schatzker… - Annual review of …, 2020 - annualreviews.org
The conscious perception of the hedonic sensory properties of caloric foods is commonly
believed to guide our dietary choices. Current and traditional models implicate the …

Metabolic and endocrine consequences of bariatric surgery

I Cornejo-Pareja, M Clemente-Postigo… - Frontiers in …, 2019 - frontiersin.org
Obesity is one of the most serious worldwide epidemics of the twenty-first century according
to the World Health Organization. Frequently associated with a number of comorbidities …

Systematic review of olfactory shifts related to obesity

M Peng, D Coutts, T Wang, YO Cakmak - Obesity reviews, 2019 - Wiley Online Library
Objective The modern food environment is a key driver of rising levels of obesity. While
olfaction is known to play a major role in food choice; however, its relationship to obesity is …

The neural basis of sugar preference

WW Liu, DV Bohórquez - Nature Reviews Neuroscience, 2022 - nature.com
When it comes to food, one tempting substance is sugar. Although sweetness is detected by
the tongue, the desire to consume sugar arises from the gut. Even when sweet taste is …

Regulation of systemic metabolism by the autonomic nervous system consisting of afferent and efferent innervation

J Imai, H Katagiri - International immunology, 2022 - academic.oup.com
Autonomic nerves, sympathetic and parasympathetic, innervate organs and modulate their
functions. It has become evident that afferent and efferent signals of the autonomic nervous …

Vagus nerve stimulation at the interface of brain–gut interactions

B Bonaz, V Sinniger… - Cold Spring …, 2019 - perspectivesinmedicine.cshlp.org
The vagus nerve, a key component of the cross-communication between the gut and the
brain, is a major element of homeostasis sensing the “milieu intérieur” and boosting the …

Roles for the gut microbiota in regulating neuronal feeding circuits

BY Kristie, EY Hsiao - The Journal of clinical investigation, 2021 - Am Soc Clin Investig
The gut microbiota has the capacity to affect host appetite via intestinal satiety pathways, as
well as complex feeding behaviors. In this Review, we highlight recent evidence that the gut …