The role of glucagon‐like peptide 1 (GLP‐1) in addictive disorders
MK Klausen, M Thomsen, G Wortwein… - British Journal of …, 2022 - Wiley Online Library
Drug, alcohol and tobacco use disorders are a global burden affecting millions of people.
Despite decades of research, treatment options are sparse or missing, and relapse rates are …
Despite decades of research, treatment options are sparse or missing, and relapse rates are …
GLP-1a: going beyond traditional use
LF Laurindo, SM Barbalho, EL Guiguer… - International Journal of …, 2022 - mdpi.com
Glucagon-like peptide-1 (GLP-1) is a human incretin hormone derived from the proglucagon
molecule. GLP-1 receptor agonists are frequently used to treat type 2 diabetes mellitus and …
molecule. GLP-1 receptor agonists are frequently used to treat type 2 diabetes mellitus and …
[HTML][HTML] The glucagon-like peptide-1 (GLP-1) analogue semaglutide reduces alcohol drinking and modulates central GABA neurotransmission
Growing evidence indicates that the glucagon-like peptide-1 (GLP-1) system is involved in
the neurobiology of addictive behaviors, and GLP-1 analogues may be used for the …
the neurobiology of addictive behaviors, and GLP-1 analogues may be used for the …
Recovery of Bacteroides thetaiotaomicron ameliorates hepatic steatosis in experimental alcohol-related liver disease
M Sangineto, C Grander, F Grabherr, L Mayr… - Gut …, 2022 - Taylor & Francis
Alcohol-related liver disease (ALD) is a major cause of liver disease and represents a global
burden, as treatment options are scarce. Whereas 90% of ethanol abusers develop …
burden, as treatment options are scarce. Whereas 90% of ethanol abusers develop …
Phasic dopamine responses to a food-predictive cue are suppressed by the glucagon-like peptide-1 receptor agonist Exendin-4
Phasic dopamine activity is evoked by reliable predictors of food reward and plays a role in
cue-triggered, goal-directed behavior. While this important signal is modulated by …
cue-triggered, goal-directed behavior. While this important signal is modulated by …
Use of GLP‐1 receptor agonists and subsequent risk of alcohol‐related events. A nationwide register‐based cohort and self‐controlled case series study
IK Wium‐Andersen, MK Wium‐Andersen… - Basic & Clinical …, 2022 - Wiley Online Library
Animal studies have related glucagon‐like peptide 1 receptor agonists (GLP‐1) to lower
alcohol intake. We examined whether GLP‐1 was associated with risk of alcohol‐related …
alcohol intake. We examined whether GLP‐1 was associated with risk of alcohol‐related …
The glucagon‐like peptide‐1 system is modulated by acute and chronic alcohol exposure: Findings from human laboratory experiments and a post‐mortem brain …
M Farokhnia, BD Browning, ME Crozier… - Addiction …, 2022 - Wiley Online Library
Growing evidence suggests that the glucagon‐like peptide‐1 (GLP‐1) system modulates
alcohol seeking and consumption, and GLP‐1 analogues may represent novel …
alcohol seeking and consumption, and GLP‐1 analogues may represent novel …
Differential association between the GLP1R gene variants and brain functional connectivity according to the severity of alcohol use
Growing evidence suggests that the glucagon-like peptide-1 (GLP-1) system is involved in
mechanisms underlying alcohol seeking and consumption. Accordingly, the GLP-1 receptor …
mechanisms underlying alcohol seeking and consumption. Accordingly, the GLP-1 receptor …
Converging vulnerability factors for compulsive food and drug use
Highly palatable foods and substance of abuse have intersecting neurobiological, metabolic
and behavioral effects relevant for understanding vulnerability to conditions related to food …
and behavioral effects relevant for understanding vulnerability to conditions related to food …
Social media as pharmacovigilance: The potential for patient reports to inform clinical research on glucagon-like peptide 1 (GLP-1) receptor agonists for substance …
MP Bremmer, CS Hendershot - Journal of Studies on Alcohol and Drugs, 2024 - jsad.com
The surge in popularity of semaglutide (Ozempic, Wegovy, Rybelsus) and other glucagon-
like-peptide 1 (GLP-1) receptor agonists has been accompanied by widespread reports of …
like-peptide 1 (GLP-1) receptor agonists has been accompanied by widespread reports of …