Bone, cartilage, and soft tissue regeneration is a complex spatiotemporal process recruiting
a variety of cell types, whose activity and interplay must be precisely mediated for effective …

Osteoporosis is characterized by the alteration of bone homeostasis due to an imbalance
between osteoclastic bone resorption and osteoblastic bone formation. Estrogen deficiency …

Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …

(1) Background: Vitamin D is an immunoregulatory factor influencing intestinal homeostasis.
Recent evidence supports a central role of this micronutrient in the course of Inflammatory …

Simple Summary Bone is an extremely metabolically active tissue that is regenerated and
repaired over its lifetime by bone remodeling. Most bone diseases are caused by abnormal …

During aging and after traumatic injuries, cartilage and bone cells are exposed to various
pathophysiologic mediators, including reactive oxygen species (ROS), damage-associated …

Background Osteoporosis and atherosclerosis are common in the elderly population,
conferring a heavy worldwide burden. Evidence links osteoporosis and atherosclerosis but …

The prevalence of osteoporosis among women aged 50 y and older is expected to reach
13.6 million by 2030. Alternative nonpharmaceutical agents for osteoporosis, including …

Background and objective This study aimed to identify crosstalk genes between periodontitis
(PD) and osteoporosis (OP) and potential relationships between crosstalk and pyroptosis …

Fracture-related infection (FRI) is a devastating complication in orthopedic surgery. A recent
study showed that FRI causes more severe infection and further delays healing in …