Background Airway oedema (swelling) and mucus plugging are the principal pathological
features in infants with acute viral bronchiolitis. Nebulised hypertonic saline solution (≥ 3%) …

BACKGROUND AND OBJECTIVE: The mainstay of treatment for acute bronchiolitis remains
supportive care. The objective of this study was to assess the efficacy and safety of …

Importance Two previous meta-analyses of nebulized hypertonic saline (HS) on hospital
length of stay (LOS) in acute viral bronchiolitis have suggested benefit. Neither study fully …

Background Acute bronchiolitis is the commonest cause of hospitalisation in infancy.
Currently management consists of supportive care and oxygen. A Cochrane review …

Background: This study evaluated the efficacy and safety of 3% nebulized hypertonic saline
(NHS) in infants with acute bronchiolitis (AB). Methods: We systematically searched the …

We undertook a cumulative meta‐analysis for the efficacy of hypertonic saline (HS)
compared to normal saline (NS) inhalations or no inhalations as controls in bronchiolitis. We …

Background Inhaled hypertonic saline (HS) has shown benefit in decreasing airway edema
in acute bronchiolitis which is the most common lower respiratory infection resulting in …

METHODS: We used the cohort of studies identified in previously published conventional
meta-analyses. Included studies were those in which authors compared treatment with HS …

Introduction The efficacy of nebulized hypertonic saline (HS) therapy for shortening hospital
length of stay (LOS) or improving bronchiolitic symptoms remains controversial. Most studies …

A meta‑analysis was performed to analyze the efficacy of 3% hypertonic saline (HS) in
bronchiolitis. Pubmed and MEDLINE databases were searched for relevant articles. A total …