Radiation-induced oral mucositis (RIOM) is a major dose-limiting toxicity in head and neck
cancer patients. It is a normal tissue injury caused by radiation/radiotherapy (RT), which has …

Cytokines function in many roles that are highly relevant to radiation research. This review
focuses on how cytokines are structurally organized, how they are induced by radiation, and …

People may be exposed to ionizing radiation during radiotherapy or following exposure to
radionuclides in nuclear medicine. Radioprotective agents have been used to reduce …

Only two radioprotective compounds, amifostine and palifermin, currently have the US FDA
approval for use in radiation therapy. However, several agents have been reported that …

Abstract Stone, HB, Moulder, JE, Coleman, CN, Ang, KK, Anscher, MS, Barcellos-Hoff, MH,
Dynan, WS, Fike, JR, Grdina, DJ, Greenberger, JS, Hauer-Jensen, M., Hill, RP, Kolesnick …

Oxidative stress, involved in many diseases, is defined as an impaired balance between
reactive oxygen species (ROS) production and antioxidant defences. Antioxidant enzymes …

Radioprotectors are compounds that protect against radiation injury when given prior to
radiation exposure. Mitigators can protect against radiation injury when given after exposure …

The ability to prevent radiotherapy-induced toxicity without affecting antitumor efficacy has
the potential to enhance the therapeutic benefit for cancer patients without increasing their …

Radiation therapy (RT) is an important therapeutic modality in the treatment of thoracic
tumors. The maximum doses to these tumors are often limited by the radiation tolerance of …

Due to the increased use of ionizing radiation in various aspects of human life especially in
areas pertaining to radiotherapy of cancer, food preservation, agriculture, industry and …