Epidemiological, migration, intervention, and genetic studies in humans and animals
provide very strong evidence of a causal link between high salt intake and high blood …

Increasingly, primary hypertension is being considered a syndrome and not a disease, with
the individual causes (diseases) having a common sign—an elevated blood pressure. To …

Only one third of patients with juvenile-onset insulin-dependent diabetes seem to be
susceptible to diabetic nephropathy. To test whether this susceptibility is related to a …

Predisposition to hypertension: Risk factor for nephropathy and hypertension in IDDM. Less
than a quarter of the patients with juvenile-onset IDDM develop diabetic nephropathy during …

Reviewed in the present article are over 150 family history studies of essential hypertension.
By comparing normotensive individuals with and without a family history of hypertension …

Abstract Background and Methods. The kidney is important in blood-pressure regulation, but
its role in the development of essential hypertension is still subject to debate. We compared …

Non-modulation is a trait characterized by abnormal angiotensin-mediated control of
aldosterone release and the renal blood supply. To determine whether non-modulation …

Many patients with essential hypertension respond to a high dietary sodium intake with a
rise in blood pressure. Experimental evidence suggests that the renal hemodynamic …

Nearly one-third of the world's population has hypertension. The human and societal impact
of hypertension is enormous. Primary hypertension accounts for 95% of cases of …

Excerpt New evidence shows that systemic and intrarenal hemodynamic abnormalities are
major factors in the initiation and progression of diabetic nephropathy. Genetic …