An integrative view on sex differences in brain tumors

T Sun, A Plutynski, S Ward, JB Rubin - Cellular and molecular life sciences, 2015 - Springer
Sex differences in human health and disease can range from undetectable to profound.
Differences in brain tumor rates and outcome are evident in males and females throughout …

Epigenetic disorders and altered gene expression after use of assisted reproductive technologies in domestic cattle

R Urrego, N Rodriguez-Osorio, H Niemann - Epigenetics, 2014 - Taylor & Francis
The use of Assisted Reproductive Technologies (ARTs) in modern cattle breeding is an
important tool for improving the production of dairy and beef cattle. A frequently employed …

Risk of major congenital malformations in relation to maternal overweight and obesity severity: cohort study of 1.2 million singletons

M Persson, S Cnattingius, E Villamor, J Söderling… - bmj, 2017 - bmj.com
Objective To estimate the risks of major congenital malformations in the offspring of mothers
who are underweight (body mass index (BMI)< 18.5), overweight (BMI 25 to< 30), or in …

Sex determines the expression level of one third of the actively expressed genes in bovine blastocysts

P Bermejo-Alvarez, D Rizos, D Rath… - Proceedings of the …, 2010 - National Acad Sciences
Although genetically identical for autosomal Chrs (Chr), male and female preimplantation
embryos could display sex-specific transcriptional regulation. To illustrate sex-specific …

Consequences of In Vitro Culture Conditions on Embryo Development and Quality

D Rizos, M Clemente… - … in Domestic Animals, 2008 - Wiley Online Library
Contents Despite major efforts directed at improving the yield of blastocysts from immature
oocytes in vitro, the quality of such blastocysts continually lags behind that of blastocysts …

Epigenetic differences between male and female bovine blastocysts produced in vitro

P Bermejo-Alvarez, D Rizos, D Rath… - Physiological …, 2008 - journals.physiology.org
Epigenetic differences between male and female bovine blastocysts provide a plausible link
between physiological and gene transcription differences observed between male and …

Use of a mouse in vitro fertilization model to understand the developmental origins of health and disease hypothesis

SK Feuer, X Liu, A Donjacour, W Lin… - …, 2014 - academic.oup.com
The Developmental Origins of Health and Disease hypothesis holds that alterations to
homeostasis during critical periods of development can predispose individuals to adult …

The mammalian preimplantation embryo: its role in the environmental programming of postnatal health and performance

MA Velazquez, A Idriss, P Chavatte-Palmer… - Animal Reproduction …, 2023 - Elsevier
During formation of the preimplantation embryo several cellular and molecular milestones
take place, making the few cells forming the early embryo vulnerable to environmental …

[PDF][PDF] Transcriptional sexual dimorphism during preimplantation embryo development and its consequences for developmental competence and adult health and …

P Bermejo-Alvarez, D Rizos, P Lonergan… - …, 2011 - researchgate.net
In adult tissues, sexual dimorphism is largely attributed to sex hormone effects, although
there is increasing evidence for a major role of sex chromosome dosage. During …

Genetic divergence in cellular resistance to heat shock in cattle: differences between breeds developed in temperate versus hot climates in responses of …

FF Paula-Lopes, CC Chase, YM Al-Katanani… - …, 2003 - rep.bioscientifica.com
The detrimental effects of heat stress on fertility in cattle are less pronounced in heat-tolerant
breeds. Although these genetic differences reflect differences in thermoregulation, cells from …