A primary mode of cancer prevention and early detection in the United States is the
widespread practice of screening. Although many strategies for early detection and …

Background and Objectives: It is generally accepted that inflammatory cells found in the
tumor microenvironment are involved in the neoplastic process, promoting cell proliferation …

Colorectal cancer is a serious health problem, a challenge for research, and a model for
studying the molecular mechanisms involved in its development. According to its incidence …

Drug repositioning, also known as drug repurposing, reprofiling, or rediscovery, is
considered to be one of the most promising strategies to accelerate the development of new …

Since colorectal cancer is one of the world's most common cancers, studies on its prevention
and early diagnosis are an emerging area of clinical oncology these days. For this study, a …

A large body of evidence has emerged over the past years to show the critical role played by
inflammation in the pathogenesis of several diseases including some cardiovascular …

Numerous studies have investigated the effects of folic acid supplementation on colorectal
cancer risk, but conflicting results were reported. We herein performed a meta-analysis …

Scope Colorectal cancer is an important health problem across the world. Here, we
investigated the possible antiproliferative/proapoptotic effects of bromelain (from the …

Colorectal adenoma (CRA) is the precursor lesion of colorectal cancer (CRC). Several
agents have been shown to be effective in the chemoprevention of CRA recurrence, but …

Epidemiological and experimental observations have shown that nonsteroidal anti-
inflammatory drugs especially selective cyclooxygenase-2 (COX-2) inhibitors and probiotics …