Adiponectin (APN), an adipose-derived adipokine, offers cardioprotective effects although
the precise mechanism of action remains unclear. This study was designed to examine the …

Obesity is an emerging problem worldwide. Hospitalized obese patients often have a worse
outcome than patients of normal weight, particularly in the setting of trauma and critical care …

The metabolic syndrome (MetS) is a cluster of risk factors including obesity, insulin
resistance, dyslipidemia, elevated blood pressure and glucose intolerance. The MetS …

Background Metallothioneins (MT) are low molecular weight, cysteine rich metal binding
proteins, found across genera and species, but their function (s) in abiotic stress tolerance …

Aims: Sepsis represents a profound proinflammatory response with a major contribution
from oxidative injury. Here we evaluated possible impact of heavy metal scavenger …

Background Mitochondrial aldehyde dehydrogenase (ALDH2) displays some promise in the
protection against cardiovascular diseases although its role in diabetes has not been …

Mammalian metallothionein-2A (MT2A) has received considerable attention in recent years
due to its crucial pathophysiological role in anti-oxidant, anti-apoptosis, detoxification and …

Mitochondria control various processes in cellular metabolic homeostasis, such as
adenosine triphosphate production, generation and clearance of reactive oxygen species …

OBJECTIVE Glycogen synthase kinase (GSK)-3β plays an important role in
cardiomyopathies. Cardiac-specific metallothionein-overexpressing transgenic (MT-TG) …

Background and aims Uncorrected obesity contributes to cardiac remodeling and contractile
dysfunction although the underlying mechanism remains poorly understood. Mitochondrial …