The oxytocin receptor: from intracellular signaling to behavior

B Jurek, ID Neumann - Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research

DS Quintana, A Lischke, S Grace, D Scheele… - Molecular …, 2021 - nature.com
Reports on the modulatory role of the neuropeptide oxytocin on social cognition and
behavior have steadily increased over the last two decades, stimulating considerable …

The social salience hypothesis of oxytocin

SG Shamay-Tsoory, A Abu-Akel - Biological psychiatry, 2016 - Elsevier
Oxytocin is a nonapeptide that also serves as a neuromodulator in the human central
nervous system. Over the last decade, a sizeable body of literature has examined its effects …

[HTML][HTML] Novel pharmacological targets in drug development for the treatment of anxiety and anxiety-related disorders

SB Sartori, N Singewald - Pharmacology & therapeutics, 2019 - Elsevier
Current medication for anxiety disorders is suboptimal in terms of efficiency and tolerability,
highlighting the need for improved drug treatments. In this review an overview of drugs …

Roles of oxytocin in stress responses, allostasis and resilience

Y Takayanagi, T Onaka - International journal of molecular sciences, 2021 - mdpi.com
Oxytocin has been revealed to work for anxiety suppression and anti-stress as well as for
psychosocial behavior and reproductive functions. Oxytocin neurons are activated by …

[HTML][HTML] Autism, oxytocin and interoception

E Quattrocki, K Friston - Neuroscience & Biobehavioral Reviews, 2014 - Elsevier
Autism is a pervasive developmental disorder characterized by profound social and verbal
communication deficits, stereotypical motor behaviors, restricted interests, and cognitive …

Approaching the biology of human parental attachment: Brain imaging, oxytocin and coordinated assessments of mothers and fathers

JE Swain, P Kim, J Spicer, SS Ho, CJ Dayton… - Brain research, 2014 - Elsevier
Brain networks that govern parental response to infant signals have been studied with
imaging techniques over the last 15 years. The complex interaction of thoughts and …

Oxytocin conditions intergroup relations through upregulated in-group empathy, cooperation, conformity, and defense

CKW De Dreu, ME Kret - Biological psychiatry, 2016 - Elsevier
Humans live in, rely on, and contribute to groups. Evolution may have biologically prepared
them to quickly identify others as belonging to the in-group (vs. not), to decode emotional …

Oxytocin enhances brain reward system responses in men viewing the face of their female partner

D Scheele, A Wille, KM Kendrick… - Proceedings of the …, 2013 - National Acad Sciences
The biological mechanisms underlying long-term partner bonds in humans are unclear. The
evolutionarily conserved neuropeptide oxytocin (OXT) is associated with the formation of …

Connecting prosocial behavior to improved physical health: Contributions from the neurobiology of parenting

SL Brown, RM Brown - Neuroscience & Biobehavioral Reviews, 2015 - Elsevier
Although a growing body of evidence suggests that giving to (helping) others is linked
reliably to better health and longevity for the helper, little is known about causal …