Dry powder inhalers in the digitalization era: current status and future perspectives
S Xiroudaki, A Schoubben, S Giovagnoli, DM Rekkas - Pharmaceutics, 2021 - mdpi.com
During the last decades, the term “drug delivery systems”(DDSs) has almost fully replaced
previously used terms, such as “dosage forms”, in an attempt to emphasize the importance …
previously used terms, such as “dosage forms”, in an attempt to emphasize the importance …
Spray-dried inhalable powder formulations of therapeutic proteins and peptides
Respiratory diseases are among the leading causes of morbidity and mortality worldwide.
Innovations in biochemical engineering and understanding of the pathophysiology of …
Innovations in biochemical engineering and understanding of the pathophysiology of …
Advances in pulmonary drug delivery devices for the treatment of chronic obstructive pulmonary disease
M Cazzola, F Cavalli, OS Usmani… - Expert opinion on drug …, 2020 - Taylor & Francis
Introduction Proper device selection is crucial for the clinical results of inhalation therapy.
However, none of the available devices fully conforms to the requirements for delivering …
However, none of the available devices fully conforms to the requirements for delivering …
Liposomes or extracellular vesicles: a comprehensive comparison of both lipid bilayer vesicles for pulmonary drug delivery
The rapid and non-invasive pulmonary drug delivery (PDD) has attracted great attention
compared to the other routes. However, nanoparticle platforms, like liposomes (LPs) and …
compared to the other routes. However, nanoparticle platforms, like liposomes (LPs) and …
[HTML][HTML] Pulmonary inhalation for disease treatment: Basic research and clinical translations
B Wang, L Wang, Q Yang, Y Zhang, T Qinglai, X Yang… - Materials Today Bio, 2024 - Elsevier
Pulmonary drug delivery has the advantages of being rapid, efficient, and well-targeted, with
few systemic side effects. In addition, it is non-invasive and has good patient compliance …
few systemic side effects. In addition, it is non-invasive and has good patient compliance …
Recent developments in the computational simulation of dry powder inhalers
J Capecelatro, W Longest, C Boerman… - Advanced Drug Delivery …, 2022 - Elsevier
This article reviews recent developments in computational modeling of dry powder inhalers
(DPIs). DPIs deliver drug formulations (sometimes blended with larger carrier particles) to a …
(DPIs). DPIs deliver drug formulations (sometimes blended with larger carrier particles) to a …
[HTML][HTML] Alginate aerogels by spray gelation for enhanced pulmonary delivery and solubilization of beclomethasone dipropionate
T Duong, M Vivero-Lopez, I Ardao… - Chemical Engineering …, 2024 - Elsevier
Aerogel technology is an emerging platform that offers alternative and cost-effective dry
carriers with advanced performances for the pharmaceutical industry. The innovative …
carriers with advanced performances for the pharmaceutical industry. The innovative …
Recent advances in the development of microparticles for pulmonary administration
H Jain, A Bairagi, S Srivastava, SB Singh… - Drug discovery today, 2020 - Elsevier
Highlights•The pulmonary route is an efficient route for respiratory diseases.•Technosphere
® and PulmoSphere™ are novel inhalable technologies for drug delivery.•Microparticles are …
® and PulmoSphere™ are novel inhalable technologies for drug delivery.•Microparticles are …
Drug delivery applications of three-dimensional printed (3DP) mesoporous scaffolds
Mesoporous materials are structures characterized by a well-ordered large pore system with
uniform porous dimensions ranging between 2 and 50 nm. Typical samples are zeolite …
uniform porous dimensions ranging between 2 and 50 nm. Typical samples are zeolite …
A pathway from porous particle technology toward tailoring aerogels for pulmonary drug administration
T Duong, C López-Iglesias, PK Szewczyk… - … in Bioengineering and …, 2021 - frontiersin.org
Pulmonary drug delivery has recognized benefits for both local and systemic treatments. Dry
powder inhalers (DPIs) are convenient, portable and environmentally friendly devices …
powder inhalers (DPIs) are convenient, portable and environmentally friendly devices …