The epidermal lipid barrier in microbiome–skin interaction

AK Tchoupa, D Kretschmer, B Schittek, A Peschel - Trends in Microbiology, 2023 - cell.com
The corneocyte layers forming the upper surface of mammalian skin are embedded in a
lamellar-membrane matrix which repels harmful molecules while retaining solutes from …

Microbiological insights and dermatological applications of live biotherapeutic products

J Locker, HJ Serrage, RG Ledder… - Journal of Applied …, 2024 - academic.oup.com
As our understanding of dermatological conditions advances, it becomes increasingly
evident that traditional pharmaceutical interventions are not universally effective. The …

Multi-omics signatures reveal genomic and functional heterogeneity of Cutibacterium acnes in normal and diseased skin

T Yu, X Xu, Y Liu, X Wang, S Wu, Z Qiu, X Liu, X Pan… - Cell Host & Microbe, 2024 - cell.com
Cutibacterium acnes is the most abundant bacterium of the human skin microbiome since
adolescence, participating in both skin homeostasis and diseases. Here, we demonstrate …

What is slough? Defining the proteomic and microbial composition of slough and its implications for wound healing

EC Townsend, JZA Cheong… - Wound Repair and …, 2024 - Wiley Online Library
Slough is a well‐known feature of non‐healing wounds. This pilot study aims to determine
the proteomic and microbiologic components of slough as well as interrogate the …

Comparative genomic and metagenomic investigations of the Corynebacterium tuberculostearicum species complex reveals potential mechanisms underlying …

R Salamzade, MH Swaney, LR Kalan - Microbiology Spectrum, 2023 - Am Soc Microbiol
Corynebacterium are a diverse genus and dominant member of the human skin microbiome.
Recently, we reported that the most prevalent Corynebacterium species found on skin …

Integrated analysis of facial microbiome and skin physio-optical properties unveils cutotype-dependent aging effects

C Sun, G Hu, L Yi, W Ge, Q Yang, X Yang, Y He, Z Liu… - Microbiome, 2024 - Springer
Background Our facial skin hosts millions of microorganisms, primarily bacteria, crucial for
skin health by maintaining the physical barrier, modulating immune response, and …

The Staphylococcus aureus regulatory program in a human skin-like environment

FG Costa, KB Mills, HA Crosby, AR Horswill - Mbio, 2024 - Am Soc Microbiol
Staphylococcus aureus is a Gram-positive pathogen responsible for the majority of skin and
soft tissue infections (SSTIs). S. aureus colonizes the anterior nares of approximately 20 …

A physiological perspective of the relevance of sweat biomarkers and their detection by wearable microfluidic technology: a Review

SC Morros, S Garcia-Rey, J Álvarez-Herms… - Analytica Chimica …, 2024 - Elsevier
The great majority of published microfluidic wearable platforms for sweat sensing focus on
the development of the technology to fabricate the device, the integration of sensing …

[HTML][HTML] COMPARATIVE WHOLE METAGENOME ANALYSIS IN LESIONAL AND NON-LESIONAL SCALP AREAS OF PSORIASIS CAPITIS PATIENTS AND HEALTHY …

B De Pessemier, CD López, S Taelman… - Journal of Investigative …, 2024 - Elsevier
Psoriasis is an immune-mediated inflammatory disorder, where the majority of the patients
suffer from psoriasis capitis or scalp psoriasis. Current therapeutics remain ineffective to …

[HTML][HTML] Enrichment of sweat-derived extracellular vesicles of human and bacterial origin for biomarker identification

A Zhyvolozhnyi, A Samoylenko, G Bart… - …, 2024 - ncbi.nlm.nih.gov
Sweat contains biomarkers for real-time non-invasive health monitoring, but only a few
relevant analytes are currently used in clinical practice. In the present study, we investigated …