[HTML][HTML] Relationships between neurodegeneration and vascular damage in diabetic retinopathy

MG Rossino, M Dal Monte, G Casini - Frontiers in Neuroscience, 2019 - frontiersin.org
Diabetic retinopathy (DR) is a common complication of diabetes and constitutes a major
cause of vision impairment and blindness in the world. DR has long been described …

A review of remote ischemic conditioning as a potential strategy for neural repair poststroke

W Yu, C Ren, X Ji - CNS Neuroscience & Therapeutics, 2023 - Wiley Online Library
Ischemic stroke is one of the major disabling health‐care problem and multiple different
approaches are needed to enhance rehabilitation, in which neural repair is the structural …

[HTML][HTML] Microglia exacerbate white matter injury via complement C3/C3aR pathway after hypoperfusion

LY Zhang, J Pan, M Mamtilahun, Y Zhu, L Wang… - Theranostics, 2020 - ncbi.nlm.nih.gov
Microglial activation participates in white matter injury after cerebral hypoperfusion.
However, the underlying mechanism is unclear. Here, we explore whether activated …

[HTML][HTML] Plasma lipoprotein-associated phospholipase A2 and superoxide dismutase are independent predicators of cognitive impairment in cerebral small vessel …

S Zhu, X Wei, X Yang, Z Huang, Z Chang, F Xie… - Aging and …, 2019 - ncbi.nlm.nih.gov
Lipoprotein-associated phospholipase A2 (Lp-PLA2) and superoxide dismutase (SOD) are
linked to regulating vascular/neuro-inflammation and stroke. Using a retrospective design …

[HTML][HTML] Dl-3-n-butylphthalide promotes remyelination and suppresses inflammation by regulating AMPK/SIRT1 and STAT3/NF-κB signaling in chronic cerebral …

M Li, N Meng, X Guo, X Niu, Z Zhao, W Wang… - Frontiers in aging …, 2020 - frontiersin.org
Demyelination in vascular dementia (VD) is partly attributable to inflammation induced by
chronic cerebral hypoperfusion (CCH). Remyelination contributes to the recovery of …

[HTML][HTML] Limb ischemic conditioning improved cognitive deficits via eNOS-dependent augmentation of angiogenesis after chronic cerebral hypoperfusion in rats

C Ren, N Li, S Li, R Han, Q Huang, J Hu, K Jin… - Aging and …, 2018 - ncbi.nlm.nih.gov
Intracranial and extracranial arterial stenosis, the primary cause of chronic cerebral
hypoperfusion (CCH), is a critical reason for the pathogenesis of vascular dementia and …

Pathological changes in neurovascular units: lessons from cases of vascular dementia

C Li, Y Wang, XL Yan, ZN Guo… - CNS Neuroscience & …, 2021 - Wiley Online Library
Vascular dementia (VD) is the second leading cause of dementia after Alzheimer's disease
(AD). The decrease of cerebral blood flow (CBF) to different degrees is one of the main …

Cerebral ischemia induces angiogenesis in the peri-infarct regions via Notch1 signaling activation

C Ren, Y Yao, R Han, Q Huang, H Li, B Wang, S Li… - Experimental …, 2018 - Elsevier
The Notch1 signaling pathway is considered as one of important regulators of angiogenesis
during development, but its role in cerebral ischemia-induced angiogenesis is less well …

MicroRNA-23b alleviates neuroinflammation and brain injury in intracerebral hemorrhage by targeting inositol polyphosphate multikinase

L Hu, H Zhang, B Wang, Q Ao, J Shi, Z He - International …, 2019 - Elsevier
Neuroinflammation plays a critical role in the pathogenesis of intracerebral hemorrhage
(ICH), contributing to detrimental brain injury and neurological function deficits. MicroRNA …

Role of exosomes induced by remote ischemic preconditioning in neuroprotection against cerebral ischemia

Y Li, C Ren, H Li, F Jiang, L Wang, C Xia, X Ji - Neuroreport, 2019 - journals.lww.com
Remote ischemic preconditioning (RIPC) is an effective regimen for neuroprotection in
ischemic stroke. Exosomes are extracellular vesicles released into the blood, where they …