Over the past 15 years, elegant studies have demonstrated that in certain conditions,
programed cell death resembles necrosis and depends on a unique molecular pathway with …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder of the brain, which is
characterized by the formation of extracellular amyloid plaques (or senile plaques) and …

Alzheimer's disease (AD) is a neurodegenerative disorder and is identified as the most
common cause for dementia. Despite huge global economic burden and the impact on the …

Microglial activation is a distinguished attribute in many neurodegenerative diseases of
aging. Compelling evidence suggests that neuroinflammation stimulated by microglia, the …

Alzheimer's disease (AD) is the most common cause of dementia in the elderly. Although its
pathogenesis remains unclear, studies have indicated microglia-mediated …

Background: The role of currently available drugs for Alzheimer's disease (AD) has been
controversial, with some national formularies restricting their use, and health economists …

Background/objective Alzheimer's disease (AD) is mainly characterized by decline of
cognitive functions such as memory and learning, which has a high prevalence and poor …

The endoplasmic reticulum (ER) is an important organelle involved in cellular homeostasis
and control of protein quality. Unfolded protein response (UPR) is a cellular response to ER …

Neurodegenerative diseases are a group of chronic progressive disorders characterized by
neuronal loss. Necroptosis, a recently discovered form of programmed cell death, is a cell …

It is generally accepted that the population rate of early onset Alzheimer's disease (EOAD) in
Alzheimer's disease (AD) is 1-2%. However, the true population based rate of EOAD has …