[HTML][HTML] Long non-coding RNAs regulated NF-κB signaling in cancer metastasis: Micromanaging by not so small non-coding RNAs
Cancer metastasis is a major reason for the cancer-associated deaths and a role of long non-
coding RNAs (lncRNAs) in cancer metastasis is increasingly being realized. Among the …
coding RNAs (lncRNAs) in cancer metastasis is increasingly being realized. Among the …
NF-κB in biology and targeted therapy: new insights and translational implications
Q Guo, Y Jin, X Chen, X Ye, X Shen, M Lin… - … and Targeted Therapy, 2024 - nature.com
NF-κB signaling has been discovered for nearly 40 years. Initially, NF-κB signaling was
identified as a pivotal pathway in mediating inflammatory responses. However, with …
identified as a pivotal pathway in mediating inflammatory responses. However, with …
Ubiquitination of NF-κB p65 by FBXW2 suppresses breast cancer stemness, tumorigenesis, and paclitaxel resistance
C Ren, X Han, C Lu, T Yang, P Qiao, Y Sun… - Cell Death & …, 2022 - nature.com
The F-box and WD-repeat-containing protein 2 (FBXW2) plays a crucial role as an E3 ligase
in regulating tumorigenesis. However, the functions of FBXW2 in breast cancer are still …
in regulating tumorigenesis. However, the functions of FBXW2 in breast cancer are still …
Melatonin enhances radiofrequency-induced NK antitumor immunity, causing cancer metabolism reprogramming and inhibition of multiple pulmonary tumor …
M Li, B Hao, M Zhang, RJ Reiter, S Lin… - … and Targeted Therapy, 2021 - nature.com
Surgery is the common treatment for early lung cancer with multiple pulmonary nodules, but
it is often accompanied by the problem of significant malignancy of other nodules in non …
it is often accompanied by the problem of significant malignancy of other nodules in non …
Recent developments and challenges in molecular-targeted therapy of non-small-cell lung cancer
Treatment of lung cancer with conventional therapies, which include radiation, surgery, and
chemotherapy results in multiple undesirable adverse or side effects. The major clinical …
chemotherapy results in multiple undesirable adverse or side effects. The major clinical …
Cancer genome and tumor microenvironment: Reciprocal crosstalk shapes lung cancer plasticity
Lung cancer classification and treatment has been revolutionized by improving our
understanding of driver mutations and the introduction of tumor microenvironment (TME) …
understanding of driver mutations and the introduction of tumor microenvironment (TME) …
Anticancer activity of NFκB decoy oligonucleotide-loaded nanoparticles against human lung cancer
Non-small cell lung cancer (NSCLC) is among the leading global causes of cancer-related
mortality. Current treatment options have limited efficacy and severe adverse effects …
mortality. Current treatment options have limited efficacy and severe adverse effects …
The relationship between TRAF6 and tumors
J Li, N Liu, L Tang, B Yan, X Chen, J Zhang… - Cancer Cell …, 2020 - Springer
Tumor necrosis factor receptor (TNFR)-related factors (TRAFs) are important linker
molecules in the tumor necrosis factor superfamily (TNFSF) and the Toll-like/interleukin-1 …
molecules in the tumor necrosis factor superfamily (TNFSF) and the Toll-like/interleukin-1 …
miR-16-5p regulates aerobic glycolysis and tumorigenesis of NSCLC cells via LDH-A/lactate/NF-κB signaling
Background and aim Cancer cells exhibit Warburg effect, characterized by increased
glycolysis followed by fermentative conversion of pyruvate to lactate. Upregulation of Lactate …
glycolysis followed by fermentative conversion of pyruvate to lactate. Upregulation of Lactate …
The role of α7-nAChR-mediated PI3K/AKT pathway in lung cancer induced by nicotine
Z He, Y Xu, Z Rao, Z Zhang, J Zhou, T Zhou… - Science of the Total …, 2023 - Elsevier
Nicotine enters the environment mainly through human activity, as well as natural sources.
This review article examines the increasing evidence implicating nicotine in the initiation …
This review article examines the increasing evidence implicating nicotine in the initiation …