[HTML][HTML] Virological success after 12 and 24 months of antiretroviral therapy in sub-Saharan Africa: Comparing results of trials, cohorts and cross-sectional studies …
F Taieb, Y Madec, A Cournil, E Delaporte - PloS one, 2017 - journals.plos.org
Background UNAIDS recently defined the 90-90-90 target as a way to end the HIV epidemic.
However, the proportion of virological success following antiretroviral therapy (ART) may not …
However, the proportion of virological success following antiretroviral therapy (ART) may not …
[HTML][HTML] Современные молекулярно-генетические методы исследования в эпидемиологическом надзоре за ВИЧ-инфекцией
НН Зайцева, ЕИ Ефимов, НН Носов… - Журнал …, 2014 - cyberleninka.ru
В обзоре представлен анализ данных по применению современных перспективных
лабораторных и IT технологий с целью совершенствования системы …
лабораторных и IT технологий с целью совершенствования системы …
HIV virological failure and drug resistance in a cohort of Tanzanian HIV-infected adults
Objectives There are few data on ART failure rates and drug resistance from Tanzania,
where there is a wide diversity of non-B HIV subtypes. We assessed rates and predictors of …
where there is a wide diversity of non-B HIV subtypes. We assessed rates and predictors of …
[HTML][HTML] Viral load testing and the use of test results for clinical decision making for HIV treatment in Cameroon: An insight into the clinic-laboratory interface
G Awungafac, ET Amin, A Fualefac, NF Takah… - PLoS …, 2018 - journals.plos.org
Background The viral load (VL) in patients receiving antiretroviral therapy (ART) is the best
predictor of treatment outcome. The anticipated benefits of VL monitoring depend on the …
predictor of treatment outcome. The anticipated benefits of VL monitoring depend on the …
[HTML][HTML] Nationwide estimates of viral load suppression and acquired HIV drug resistance in Cameroon
GF Tchouwa, S Eymard-Duvernay, A Cournil… - …, 2018 - thelancet.com
Background Population-based studies to estimate viral load (VL) suppression and rate of
acquired HIV drug resistance (ADR) are essential in sub-Saharan Africa. We conducted the …
acquired HIV drug resistance (ADR) are essential in sub-Saharan Africa. We conducted the …
[HTML][HTML] High level of HIV-1 drug resistance mutations in patients with unsuppressed viral loads in rural northern South Africa
EM Etta, L Mavhandu, C Manhaeve… - AIDS research and …, 2017 - Springer
Background Combination antiretroviral therapy (cART) has significantly reduced HIV
morbidity and mortality in both developed and developing countries. However, the …
morbidity and mortality in both developed and developing countries. However, the …
[HTML][HTML] Should viral load thresholds be lowered?: revisiting the WHO definition for virologic failure in patients on antiretroviral therapy in resource-limited settings
ND Labhardt, J Bader, TI Lejone, I Ringera… - Medicine, 2016 - journals.lww.com
Abstract The World Health Organization (WHO) guidelines on antiretroviral therapy (ART)
define treatment failure as 2 consecutive viral loads (VLs)≥ 1000 copies/mL. There is …
define treatment failure as 2 consecutive viral loads (VLs)≥ 1000 copies/mL. There is …
High rate of HIV resuppression after viral failure on first-line antiretroviral therapy in the absence of switch to second-line therapy
RK Gupta, RL Goodall, M Ranopa… - Clinical infectious …, 2014 - academic.oup.com
In a randomized comparison of nevirapine or abacavir with zidovudine plus lamivudine,
routine viral load monitoring was not performed, yet 27% of individuals with viral failure at …
routine viral load monitoring was not performed, yet 27% of individuals with viral failure at …
In-depth analysis of HIV-1 drug resistance mutations in HIV-infected individuals failing first-line regimens in West and Central Africa
CJ Villabona-Arenas, N Vidal, E Guichet, L Serrano… - Aids, 2016 - journals.lww.com
Objective: In resource-limited countries, antiretroviral therapy (ART) has been scaled up, but
individual monitoring is still suboptimal. Here, we studied whether or not ART had an impact …
individual monitoring is still suboptimal. Here, we studied whether or not ART had an impact …
Risk factors and mortality associated with resistance to first-line antiretroviral therapy: multicentric cross-sectional and longitudinal analyses
L Pinoges, B Schramm, E Poulet, S Balkan… - JAIDS Journal of …, 2015 - journals.lww.com
Background: Understanding the factors associated with HIV drug resistance development
and subsequent mortality is important to improve clinical patient management. Methods …
and subsequent mortality is important to improve clinical patient management. Methods …