Advance on the Flavonoid C-glycosides and Health Benefits

J Xiao, E Capanoglu, AR Jassbi… - Critical reviews in food …, 2016 - Taylor & Francis
The dietary flavonoids, especially their glycosides, are the most vital phytochemicals in diets
and are of great general interest due to their diverse bioactivity. Almost all natural flavonoids …

Targeting PI3K/Akt/mTOR signaling pathway by polyphenols: Implication for cancer therapy

M Mirza-Aghazadeh-Attari, EM Ekrami, SAM Aghdas… - Life sciences, 2020 - Elsevier
Cancer is one of the biggest challenges facing medicine and its cure is regarded to be the
Holy Grail of medicine. Therapy in cancer is consisted as various artificial cytotoxic agents …

[HTML][HTML] MALAT1 as a diagnostic and therapeutic target in diabetes-related complications: a promising long-noncoding RNA

LE Abdulle, J Hao, OP Pant, X Liu, D Zhou… - … journal of medical …, 2019 - ncbi.nlm.nih.gov
Diabetes mellitus is a global issue with increasing incidence rate worldwide. In an
uncontrolled case, it can advance to various organ-related complications leading to an …

Stability of dietary polyphenols under the cell culture conditions: Avoiding erroneous conclusions

J Xiao, P Högger - Journal of agricultural and food chemistry, 2015 - ACS Publications
Most data of bioactivity from dietary polyphenols have been derived from in vitro cell culture
experiments. In this context, little attention is paid to potential artifacts due to chemical …

Antitumor effects of polysaccharide from Sargassum fusiforme against human hepatocellular carcinoma HepG2 cells

S Fan, J Zhang, W Nie, W Zhou, L Jin, X Chen… - Food and Chemical …, 2017 - Elsevier
Abstract Sargassum fusiforme (Harv.) Setchel, a kind of brown algae, has been applied as a
therapeutic for thousands of years. This study was designed to investigate the antitumor …

Adaptive cellular stress pathways as therapeutic targets of dietary phytochemicals: focus on the nervous system

J Lee, DG Jo, D Park, HY Chung, MP Mattson - Pharmacological reviews, 2014 - ASPET
During the past 5 decades, it has been widely promulgated that the chemicals in plants that
are good for health act as direct scavengers of free radicals. Here we review evidence that …

Luteolin inhibits ROS-activated MAPK pathway in myocardial ischemia/reperfusion injury

D Yu, M Li, Y Tian, J Liu, J Shang - Life Sciences, 2015 - Elsevier
Aims Luteolin is a falconoid compound that has an antioxidant effect, but its contribution to
ROS-activated MAPK pathways in ischemia/reperfusion injury is seldom reported. Here, we …

LncRNA MALAT1 promotes the apoptosis and oxidative stress of human lens epithelial cells via p38MAPK pathway in diabetic cataract

W Gong, G Zhu, J Li, X Yang - Diabetes research and clinical practice, 2018 - Elsevier
Background LncRNAs are involved in various biological processes and disorders. We
aimed to investigate the role of lncRNA MALAT1 deregulation in the pathogenic mechanism …

Chemical characterization of Pleurotus eryngii polysaccharide and its tumor-inhibitory effects against human hepatoblastoma HepG-2 cells

D Ren, N Wang, J Guo, L Yuan, X Yang - Carbohydrate Polymers, 2016 - Elsevier
This study was designed to investigate the chemical characterization and antitumor effects of
Pleurotus eryngii polysaccharides (PEP). The crude PEP was fractionated into two fractions …

Isoorientin induces apoptosis and autophagy simultaneously by reactive oxygen species (ROS)-related p53, PI3K/Akt, JNK, and p38 signaling pathways in HepG2 …

L Yuan, S Wei, J Wang, X Liu - Journal of Agricultural and Food …, 2014 - ACS Publications
Cell death is closely related to autophagy under some circumstances; however, the effect of
isoorientin (ISO) on autophagy and the interplay between apoptosis and autophagy in …