A large number of pharmacological studies have used capsaicin as a tool to activate many
physiological systems, with an emphasis on pain research but also including functions such …

Capsaicin is the pungent ingredient of chili peppers and is approved as a topical treatment
of neuropathic pain. The analgesia lasts for several months after a single treatment …

The aim of this study was to develop a rat model of capsaicin-induced pain in the orofacial
region. We examined the effects of subcutaneous injection of different doses of capsaicin …

Capsaicin activates poorly myelinated primary afferent neurons, many of which are
polymodal nociceptors. Activation is accompanied by membrane depolarization and the …

Capsaicin produces pain by selectively activating polymodal nociceptive neurons. This
involves a membrane depolarization and the opening of a unique, cation-selective, ion …

1 Capsazepine has recently been described as a competitive capsaicin antagonist. We have
used this compound to test the hypotheses that the in vitro and in vivo effects of capsaicin …

The Transient receptor potential cation channel subfamily V member 1 (TRPV1) is a non-
selective cation channel that is activated by capsaicin, low pH and noxious heat. It has been …

Airway hyperresponsiveness of the tracheobronchial path is recognized as the critical
feature of bronchial asthma. Sensory nerves in the airway are implicated strongly in this …

Capsaicin and analogues are valuable analgesic agents when administered to mammals,
including humans. However, their pungency and the effects on the cardiovascular and …

Extracellular unitary recordings were made from 53 spinal trigeminal nucleus oralis (Sp5O)
convergent neurons in halothane‐anaesthetized rats. The neurons had an ipsilateral …