The emerging therapeutic potential of kisspeptin and neurokinin B
B Patel, K Koysombat, EG Mills, J Tsoutsouki… - Endocrine …, 2024 - academic.oup.com
Kisspeptin (KP) and neurokinin B (NKB) are neuropeptides that govern the reproductive
endocrine axis through regulating hypothalamic gonadotropin-releasing hormone (GnRH) …
endocrine axis through regulating hypothalamic gonadotropin-releasing hormone (GnRH) …
[HTML][HTML] Kisspeptin and polycystic ovary syndrome
R Tang, X Ding, J Zhu - Frontiers in endocrinology, 2019 - frontiersin.org
Although the pathogenesis of Polycystic Ovary Syndrome (PCOS) is still unclear, the
disturbance of hypothalamic-pituitary-gonadal (HPG) axis is suspected to be the main culprit …
disturbance of hypothalamic-pituitary-gonadal (HPG) axis is suspected to be the main culprit …
KNDy neurons as the GnRH pulse generator: Recent studies in ruminants
This review considers three aspects of recent work on the role of KNDy neurons in GnRH
pulse generation in ruminants. First, work on basic mechanisms of pulse generation …
pulse generation in ruminants. First, work on basic mechanisms of pulse generation …
Hypothalamus as an endocrine organ
IJ Clarke - Comprehensive Physiology, 2011 - Wiley Online Library
The endocrine hypothalamus constitutes those cells which project to the median eminence
and secrete neurohormones into the hypophysial portal blood to act on cells of the anterior …
and secrete neurohormones into the hypophysial portal blood to act on cells of the anterior …
Neural control of female sexual behaviors
Reproduction is the biological process by which new individuals are produced by their
parents. It is the fundamental feature of all known life and is required for the existence of all …
parents. It is the fundamental feature of all known life and is required for the existence of all …
[HTML][HTML] Kisspeptin and the regulation of the reproductive axis in domestic animals
The control of reproductive processes involves the integration of a number of factors from the
internal and external environment, with the final output signal of these processes being the …
internal and external environment, with the final output signal of these processes being the …
[HTML][HTML] Current perspectives on kisspeptins role in behaviour
The neuropeptide kisspeptin is now well-established as the master regulator of the
mammalian reproductive axis. Beyond the hypothalamus, kisspeptin and its cognate …
mammalian reproductive axis. Beyond the hypothalamus, kisspeptin and its cognate …
[HTML][HTML] Reproductive neuroendocrine pathways of social behavior
Social behaviors are key components of reproduction, because they are essential for
successful fertilization. Social behaviors, such as courtship, mating, and aggression, are …
successful fertilization. Social behaviors, such as courtship, mating, and aggression, are …
A role for neurokinin B in pulsatile GnRH secretion in the ewe
The recent description of infertility in humans with loss-of-function mutations in genes for
neurokinin B (NKB) or its receptor (NK3R) has focused attention on the importance of this …
neurokinin B (NKB) or its receptor (NK3R) has focused attention on the importance of this …
[HTML][HTML] Identification of an olfactory signal molecule that activates the central regulator of reproduction in goats
K Murata, S Tamogami, M Itou, Y Ohkubo… - Current Biology, 2014 - cell.com
Pheromone signals regulate conspecific behavior and physiology [1]. Releaser pheromones
induce specific behavior by exerting acute effects on the neuronal response, whereas primer …
induce specific behavior by exerting acute effects on the neuronal response, whereas primer …