Functional and clinical importance of SGLT2-inhibitors in frailty: from the kidney to the heart

G Santulli, F Varzideh, I Forzano, S Wilson… - …, 2023 - Am Heart Assoc
SGLT2 (sodium-glucose cotransporter 2) enables glucose and sodium reabsorption in the
kidney. SGLT2-inhibitors (also known as gliflozins, which include canagliflozin …

The basis for weekly insulin therapy: evolving evidence with insulin icodec and insulin efsitora alfa

J Rosenstock, R Juneja, JM Beals, JS Moyers… - Endocrine …, 2024 - academic.oup.com
Basal insulin continues to be a vital part of therapy for many people with diabetes. First
attempts to prolong the duration of insulin formulations were through the development of …

2023 ACC expert consensus decision pathway on management of heart failure with preserved ejection fraction: a report of the American College of Cardiology …

MM Kittleson, GS Panjrath, K Amancherla… - Journal of the American …, 2023 - jacc.org
The American College of Cardiology (ACC) has a long history of developing documents (eg,
decision pathways, health policy statements, appropriate use criteria) to provide members …

Optimal dose and type of physical activity to improve glycemic control in people diagnosed with type 2 diabetes: a systematic review and meta-analysis

D Gallardo-Gómez, E Salazar-Martínez… - Diabetes …, 2024 - Am Diabetes Assoc
BACKGROUND The optimal dose or type of physical activity to control glycosylated
hemoglobin (HbA1c) in people with diabetes remains unknown. Current guidelines do not …

Extended-release metformin improves cognitive impairment in frail older women with hypertension and diabetes: preliminary results from the LEOPARDESS Study

P Mone, G Martinelli, A Lucariello, AL Leo… - Cardiovascular …, 2023 - Springer
Background Women have a high risk of frailty independently of age and menopause state.
Diabetes and hypertension increase the risk of frailty and cognitive impairment. Metformin …

Starch-ascorbyl palmitate inclusion complex, a type 5 resistant starch, reduced in vitro digestibility and improved in vivo glycemic response in mice

J Guo, A Ellis, Y Zhang, L Kong, L Tan - Carbohydrate Polymers, 2023 - Elsevier
The prevalence of type 2 diabetes (T2D) has become a major public health concern
worldwide. Slowly digested or indigestible carbohydrates such as resistant starch (RS) are …

The usefulness of the retina for identifying people with type 2 diabetes with prodromal stages of dementia

A Ciudin, C Hernandez, O Simó-Servat… - … & Biobehavioral Reviews, 2024 - Elsevier
Abstract Type 2 diabetes (T2D) is associated with cognitive impairment and dementia. The
detection of cognitive impairment is important because this population is at higher risk of …

The association between TyG and all-cause/non-cardiovascular mortality in general patients with type 2 diabetes mellitus is modified by age: results from the cohort …

Y Yao, B Wang, T Geng, J Chen, W Chen… - Cardiovascular …, 2024 - Springer
Background The prognostic value of triglyceride-glucose (TyG) index in general type 2
diabetes mellitus (T2DM) patients is still unclear. Therefore, we aimed to determine the …

Utility of the NIH Toolbox Cognition Battery in middle to older aged adults with longstanding type 1 diabetes: the DCCT/EDIC study

NS Chaytor, VR Trapani, BH Braffett… - The Clinical …, 2024 - Taylor & Francis
Objective: Adults with type 1 diabetes (T1D) face an increased risk for cognitive decline and
dementia. Diabetes-related and vascular risk factors have been linked to cognitive decline …

Cardiorenal outcomes and mortality after sodium‐glucose cotransporter‐2 inhibitor initiation in type 2 diabetes patients with percutaneous coronary intervention …

JH Kim, YS Lyu, BS Kim, MK Kim… - Diabetes, Obesity …, 2024 - Wiley Online Library
Aims To evaluate the effects of initiating sodium‐glucose cotransporter‐2 (SGLT2) inhibitors
on cardiorenal outcomes and mortality compared to dipeptidyl peptidase‐4 (DPP‐4) …