Kidney transplantation is the treatment of choice for patients with kidney failure. Compared
to dialysis therapy, it provides better quality of life and confers significant survival advantage …

The damage of the endothelial glycocalyx as a consequence of ischemia and/or reperfusion
injury (IRI) following kidney transplantation has come at the spotlight of research due to …

Purpose of review Antibody-mediated rejection is the leading cause of deterioration of graft
function and graft loss after kidney transplantation. Recent studies have reported an …

Cardiovascular disease (CVD) and its complications are a leading cause of death
worldwide. Endothelial dysfunction plays a crucial role in the initiation and progression of …

Objectives: Hypertension is one of the major adverse effects of tyrosine kinase inhibitors
(TKIs) targeting vascular endothelial growth factors. However, the mechanism underlying …

Objective To explore the effects and possible mechanisms of the drug pair Cornus officinalis
and Radix achyranthis bidentatae (SYR-NX) on improving hypertensive kidney damage …

Nitric oxide (NO) is the first identified member of the gasotransmitter family. It is synthesized
by a group of enzymes called nitric oxide synthases (NOS). Three structurally distinct …

Gasotransmitters are a class of small endogenously produced gaseous signaling molecules.
They are dissolved gases in blood and other body fluids, and play important roles in cellular …

Objectives Ischemic stroke is a common and debilitating disease that can cause permanent
neurological damage. Gucy1a3, which encodes the α1 subunit of soluble guanylyl cyclase …

Chronic renal insufficiency (CRI) is characterized by increased endothelin 1 (ET-1)
synthesis. We studied rat kidney endothelin receptor A (ETA) and receptor B (ETB) …