[HTML][HTML] In vivo small animal micro-CT using nanoparticle contrast agents

JR Ashton, JL West, CT Badea - Frontiers in pharmacology, 2015 - frontiersin.org
Computed tomography (CT) is one of the most valuable modalities for in vivo imaging
because it is fast, high-resolution, cost-effective, and non-invasive. Moreover, CT is heavily …

Preclinical anatomical, molecular, and functional imaging of the lung with multiple modalities

ST Gammon, N Foje, EM Brewer… - … of Physiology-Lung …, 2014 - journals.physiology.org
In vivo imaging is an important tool for preclinical studies of lung function and disease. The
widespread availability of multimodal animal imaging systems and the rapid rate of …

Optimizing energy transfer in nanostructures enables in vivo cancer lesion tracking via near‐infrared excited hypoxia imaging

Y Li, J Liu, Z Wang, J Jin, Y Liu, C Chen… - Advanced …, 2020 - Wiley Online Library
To explore highly sensitive and low‐toxicity techniques for tracking and evaluation of non‐
small‐cell lung cancer (NSCLC), one of the most mortal tumors in the world, it is utterly …

[HTML][HTML] Micro-CT-derived ventilation biomarkers for the longitudinal assessment of pathology and response to therapy in a mouse model of lung fibrosis

F Pennati, L Leo, E Ferrini, N Sverzellati, D Bernardi… - Scientific Reports, 2023 - nature.com
Experimental in-vivo animal models are key tools to investigate the pathogenesis of lung
disease and to discover new therapeutics. Histopathological and biochemical investigations …

[HTML][HTML] Optimization of microCT imaging and blood vessel diameter quantitation of preclinical specimen vasculature with radiopaque polymer injection medium

SX Vasquez, F Gao, F Su, V Grijalva, J Pope, B Martin… - PloS one, 2011 - journals.plos.org
Vascular networks within a living organism are complex, multi-dimensional, and challenging
to image capture. Radio-angiographic studies in live animals require a high level of …

[HTML][HTML] Preclinical mouse models of osteosarcoma

Ö Uluçkan, A Segaliny, S Botter, JM Santiago… - BoneKEy …, 2015 - ncbi.nlm.nih.gov
Osteosarcoma is the most common form of primary bone tumors with high prevalence in
children. Survival rates of osteosarcoma are low, especially in the case of metastases …

[HTML][HTML] Detection of lung nodules in micro-CT imaging using deep learning

MD Holbrook, DP Clark, R Patel, Y Qi, AM Bassil… - Tomography, 2021 - mdpi.com
We are developing imaging methods for a co-clinical trial investigating synergy between
immunotherapy and radiotherapy. We perform longitudinal micro-computed tomography …

[HTML][HTML] Time-to-progression of NSCLC from early to advanced stages: an analysis of data from SEER registry and a single institute

P Yuan, JL Cao, A Rustam, C Zhang, XS Yuan… - Scientific reports, 2016 - nature.com
The average time required for cancers to progress through stages can be reflected in the
average age of the patients diagnosed at each stage of disease. To estimate the time it takes …

Quantitative monitoring of mouse lung tumors by magnetic resonance imaging

AS Krupnick, VK Tidwell, JA Engelbach, VV Alli… - nature protocols, 2012 - nature.com
Primary lung cancer remains the leading cause of cancer-related death in the Western
world, and the lung is a common site for recurrence of extrathoracic malignancies. Small …

[HTML][HTML] Deep learning based automated orthotopic lung tumor segmentation in whole-body mouse CT-scans

WRPH van de Worp, B van der Heyden, G Lappas… - Cancers, 2021 - mdpi.com
Simple Summary The development of more translatable orthotopic mouse models is
essential in order to study lung cancer more realistically. However, a major challenge in …