Optimization strategies for mesenchymal stem cell-based analgesia therapy: a promising therapy for pain management
J Zhang, P Wu, Q Wen - Stem Cell Research & Therapy, 2024 - Springer
Pain is a very common and complex medical problem that has a serious impact on
individuals' physical and mental health as well as society. Non-steroidal anti-inflammatory …
individuals' physical and mental health as well as society. Non-steroidal anti-inflammatory …
Impact of inflammation and Treg cell regulation on neuropathic pain in spinal cord injury: mechanisms and therapeutic prospects
C Zhang, Y Li, Y Yu, Z Li, X Xu, Z Talifu, W Liu… - Frontiers in …, 2024 - frontiersin.org
Spinal cord injury is a severe neurological trauma that can frequently lead to neuropathic
pain. During the initial stages following spinal cord injury, inflammation plays a critical role; …
pain. During the initial stages following spinal cord injury, inflammation plays a critical role; …
Glucose competition between endothelial cells in the blood-spinal cord barrier and infiltrating regulatory T cells is linked to sleep restriction-induced hyperalgesia
Y Huang, R Xu, Q Liu, X Zhang, Y Mao, Y Yang, X Gu… - BMC medicine, 2024 - Springer
Background Sleep loss is a common public health problem that causes hyperalgesia,
especially that after surgery, which reduces the quality of life seriously. Methods The 48-h …
especially that after surgery, which reduces the quality of life seriously. Methods The 48-h …
[HTML][HTML] Inhibition of aquaporin-4 and its subcellular localization attenuates below-level central neuropathic pain by regulating astrocyte activation in a rat spinal cord …
Y Song, T Xue, S Guo, Z Yu, C Yun, J Zhao, Z Song… - …, 2024 - Elsevier
The mechanisms of central neuropathic pain (CNP) caused by spinal cord injury have not
been sufficiently studied. We have found that the upregulation of astrocytic aquaporin-4 …
been sufficiently studied. We have found that the upregulation of astrocytic aquaporin-4 …
Involvement of interferon gamma signaling in spinal trigeminal caudal subnucleus astrocyte in orofacial neuropathic pain in rats with infraorbital nerve injury
S Asano, A Okada-Ogawa, M Kobayashi… - Molecular …, 2023 - journals.sagepub.com
Background: Trigeminal nerve injury causes orofacial pain that can interfere with activities of
daily life. However, the underlying mechanism remains unknown, and the appropriate …
daily life. However, the underlying mechanism remains unknown, and the appropriate …
Hyperbaric oxygen attenuates chronic postsurgical pain by regulating the CD73/adenosine/A1R axis of the spinal cord in rats
L Yin, W Liu, Z Zhang, J Zhang, H Chen, L Xiong - The Journal of Pain, 2024 - Elsevier
Chronic postsurgical pain (CPSP) affects postoperative rehabilitation and quality of life in
patients, but its mechanisms are still poorly understood. Hyperbaric oxygen (HBO) …
patients, but its mechanisms are still poorly understood. Hyperbaric oxygen (HBO) …