The endothelium can evoke relaxations of the underlying vascular smooth muscle, by
releasing vasodilator substances. The best‐characterized endothelium‐derived relaxing …

Objective (s): Metabolic syndrome, a coexisting of high blood glucose, obesity, dyslipidemia
and hypertension, is an important risk factor for cardiovascular disease occurrence and …

TRPV1 has been originally cloned as the heat and capsaicin receptor implicated in acute
pain signalling, while further research has shifted the focus to its importance in chronic pain …

Background: Sustained Hif1α (hypoxic-inducible factor-1 alpha) accumulation plays a
central role in osteogenic transdifferentiation and subsequent calcification. Capsaicin, the …

Nephropathic patients show elevated cardiovascular morbidity and mortality compared to
the general population. In order to delve deeper into the understanding of this phenomenon …

Purpose The aim of our study was to explore the association between frequency of spicy
food consumption and risk of hypertension in Chinese adults. Methods Data were extracted …

Background & aims The present systematic review and meta-analysis were conducted to
investigate the effects of capsinoids and fermented red pepper paste (FRPP) …

The formation of fat-laden foam cells, contributing to the fatty streaks of the plaques of
atheroma, is the critical early process in atherosclerosis. The previous study demonstrated …

Stroke is a common critical disease occurring in middle‑aged and elderly individuals, and is
characterized by high morbidity, lethality and mortality. As such, it is of great concern to …

Hypertension is the most important risk factor for cardiovascular diseases worldwide.
However, the underlying molecular mechanisms of hypertension are complex and remain …