Purpose Women with BRCA1/2 mutations inherit high risks of breast and ovarian cancer;
options to reduce cancer mortality include prophylactic surgery or breast screening, but their …

Background It has become increasingly common to consider BRCA mutation status when
determining optimal cancer risk management and treatment options in order to improve …

Opinion statement Breast cancer effects nearly 200,000 American women each year, with
9% of these women still in their childbearing years. For this subset of future survivors, the …

Expanded genetic testing of BRCA mutations has led to identification of more reproductive-
aged women who test positive for the mutation which might impact attitudes and decisions …

STUDY QUESTION How do couples with a BRCA1/2 mutation decide on preimplantation
genetic diagnosis (PGD) and prenatal diagnosis (PND) for hereditary breast and ovarian …

The scope of conditions for which preimplantation genetic diagnosis (PGD) is licensed has
recently been expanded in the United Kingdom to include genetic predisposition to adult …

Purpose Women with BRCA1 or BRCA2 (BRCA1/2) mutations must choose between
prophylactic surgeries and screening to manage their high risks of breast and ovarian …

Preimplantation genetic diagnosis (PGD) allows couples to avoid having a child with an
inherited condition, potentially reducing cancer burden in families with a hereditary cancer …

STUDY QUESTION How do young women, who were identified as carrying a BRCA gene
mutation before they had children, approach reproductive decision-making and what are …

Women who test positive for a BRCA genetic mutation are at an increased risk for
developing hereditary breast and ovarian cancer and have a 50% chance of passing on …