Diversity and complexity of cell death: a historical review

W Park, S Wei, BS Kim, B Kim, SJ Bae… - … & molecular medicine, 2023 - nature.com
Death is the inevitable fate of all living organisms, whether at the individual or cellular level.
For a long time, cell death was believed to be an undesirable but unavoidable final outcome …

Epigallocatechin 3-gallate: From green tea to cancer therapeutics

M Alam, S Ali, GM Ashraf, AL Bilgrami, DK Yadav… - Food chemistry, 2022 - Elsevier
Abstract Epigallocatechin 3-gallate (EGCG) possesses various biological functions,
including anti-cancer and anti-inflammatory properties. EGCG is an abundant polyphenolic …

[HTML][HTML] Pharmacological basis and new insights of quercetin action in respect to its anti-cancer effects

SM Tang, XT Deng, J Zhou, QP Li, XX Ge… - Biomedicine & …, 2020 - Elsevier
Quercetin is a kind of flavonoid compounds that comes from nature and is widely existed in
the daily diet. Previous studies have found that quercetin has many effects such as anti …

[HTML][HTML] Understanding apoptosis and apoptotic pathways targeted cancer therapeutics

R Jan - Advanced pharmaceutical bulletin, 2019 - ncbi.nlm.nih.gov
Various physiological processes involve appropriate tissue developmental process and
homeostasis-the pathogenesis of several diseases connected with deregulatory apoptosis …

Anti-cancer natural products and their bioactive compounds inducing ER stress-mediated apoptosis: A review

C Kim, B Kim - Nutrients, 2018 - mdpi.com
Cancer is the second biggest cause of death worldwide. Despite a number of studies being
conducted, the effective mechanism for treating cancer has not yet been fully understood …

Protective effects of natural polysaccharides on intestinal barrier injury: A review

J Huo, Z Wu, W Sun, Z Wang, J Wu… - Journal of agricultural …, 2022 - ACS Publications
Owing to their minimal side effects and effective protection from oxidative stress,
inflammation, and malignant growth, natural polysaccharides (NPs) are a potential adjuvant …

ATF3/SPI1/SLC31A1 signaling promotes cuproptosis induced by advanced glycosylation end products in diabetic myocardial injury

S Huo, Q Wang, W Shi, L Peng, Y Jiang, M Zhu… - International Journal of …, 2023 - mdpi.com
Cuproptosis resulting from copper (Cu) overload has not yet been investigated in diabetic
cardiomyopathy (DCM). Advanced glycosylation end products (AGEs) induced by persistent …

Ru (II) compounds: next-generation anticancer metallotherapeutics?

S Thota, DA Rodrigues, DC Crans… - Journal of medicinal …, 2018 - ACS Publications
Metal based therapeutics are a precious class of drugs in oncology research that include
examples of theranostic drugs, which are active in both diagnostic, specifically imaging, and …

Major apoptotic mechanisms and genes involved in apoptosis

Y Kiraz, A Adan, M Kartal Yandim, Y Baran - Tumor Biology, 2016 - Springer
As much as the cellular viability is important for the living organisms, the elimination of
unnecessary or damaged cells has the opposite necessity for the maintenance of …

Multiple myeloma: Available therapies and causes of drug resistance

V Pinto, R Bergantim, HR Caires, H Seca… - Cancers, 2020 - mdpi.com
Multiple myeloma (MM) is the second most common blood cancer. Treatments for MM
include corticosteroids, alkylating agents, anthracyclines, proteasome inhibitors …