Barriers associated with direct muscle quantification have prevented a consistent
implementation of therapeutic measures for sarcopenia. Recently, the relevance of …

Sex steroids influence the maintenance and growth of muscles. Decline in androgens,
estrogens and progesterone by aging leads to the loss of muscular function and mass …

Abstract Background C‐terminal Agrin Fragment (CAF) has been proposed as a novel
biomarker for sarcopenia originating from the degeneration of the neuromuscular junctions …

The two most common muscle wasting diseases in adults are sarcopenia and cachexia.
Despite differences in their pathophysiology, it is believed that both conditions are likely to …

Basic research has revealed that maintenance of neuromuscular junctions and a few
signaling pathways are important in the context of age-dependent and other forms of muscle …

Motor neuron degeneration, denervation, neuromuscular junction (NMJ) fragmentation and
loss of motor units (MUs), play a key-role in the development of sarcopenia. The aim of the …

The neuromuscular junction (NMJ) is a specialized chemical synapse that converts neural
impulses into muscle action. Age-associated NMJ degeneration, which involves nerve …

The objective of this systematic review and meta-analysis was to determine if there are sex-
based differences in adaptations to resistance exercise training in healthy older adults …

The study aimed to evaluate the impact of selected exerkines concentration induced by folk-
dance and balance training on physical performance, insulin resistance, and blood pressure …

The complexities and heterogeneity of the ageing process have slowed the development of
consensus on appropriate biomarkers of healthy ageing. The Medical Research Council …