[HTML][HTML] From cell lines to pluripotent stem cells for modelling Parkinson's Disease
Parkinson's disease (PD) is the second most common neurodegenerative disorder
characterized by loss of dopaminergic (DAergic) neurons in the substantia nigra (SN) that …
characterized by loss of dopaminergic (DAergic) neurons in the substantia nigra (SN) that …
Pre-Clinical studies identifying molecular pathways of neuroinflammation in Parkinson's disease: a systematic review
Parkinson's disease (PD), the second most common neurodegenerative disorder, is
characterized by neuroinflammation, formation of Lewy bodies, and progressive loss of …
characterized by neuroinflammation, formation of Lewy bodies, and progressive loss of …
Transcriptome Highlights Cannabinol Modulation of Mitophagy in a Parkinson's Disease In Vitro Model
A Gugliandolo, S Blando, S Salamone, F Pollastro… - Biomolecules, 2023 - mdpi.com
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the loss of
dopaminergic neurons in the substantia nigra and the accumulation of α-synuclein …
dopaminergic neurons in the substantia nigra and the accumulation of α-synuclein …
Combining automated organoid workflows with artificial intelligence‐based analyses: opportunities to build a new generation of interdisciplinary high‐throughput …
H Renner, HR Schöler, JM Bruder - Movement Disorders, 2021 - Wiley Online Library
Parkinson's disease (PD) is the second most common neurodegenerative disease and
primarily characterized by the loss of dopaminergic neurons in the substantia nigra pars …
primarily characterized by the loss of dopaminergic neurons in the substantia nigra pars …
Organs-on-a-Chip
LA Low, M Sutherland, N Lumelsky, S Selimovic… - … -and Microfluidics-Based …, 2020 - Springer
Organs-on-chips, also known as “tissue chips” or microphysiological systems (MPS), are
bioengineered microsystems capable of recreating aspects of human organ physiology and …
bioengineered microsystems capable of recreating aspects of human organ physiology and …
Parkinson's disease and the gut: Models of an emerging relationship
Parkinson's disease (PD) is a common neurodegenerative disease characterized by a
progressive loss of fine motor function that impacts 1-2 out of 1,000 people. PD occurs …
progressive loss of fine motor function that impacts 1-2 out of 1,000 people. PD occurs …
Dictyostelium discoideum as a Model for Investigating Neurodegenerative Diseases
HN Haver, KM Scaglione - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
The social amoeba Dictyostelium discoideum is a model organism that is used to investigate
many cellular processes including chemotaxis, cell motility, cell differentiation, and human …
many cellular processes including chemotaxis, cell motility, cell differentiation, and human …
[HTML][HTML] Unraveling brain diseases: the promise of brain-on-a-chip models
Brain disorders, encompassing a wide spectrum of neurological and psychiatric conditions,
present a formidable challenge in modern medicine. Despite decades of research, the …
present a formidable challenge in modern medicine. Despite decades of research, the …
In vitro and in vivo models for anti-amyloidosis nanomedicines
Amyloid diseases are global epidemics characterized by the accumulative deposits of cross-
beta amyloid fibrils and plaques. Despite decades of intensive research, few solutions are …
beta amyloid fibrils and plaques. Despite decades of intensive research, few solutions are …
Quantifying microglial phagocytosis of apoptotic cells in the brain in health and disease
S Beccari, I Diaz‐Aparicio… - Current protocols in …, 2018 - Wiley Online Library
Apoptosis is a ubiquitous process occurring in the brain under both physiological and
pathological conditions. The central nervous system (CNS) requires an active and efficient …
pathological conditions. The central nervous system (CNS) requires an active and efficient …