Einfluss einer mTOR-Überaktivierung auf die neuronale Zellmorphologie in-vitro

J Ludwig - 2023 - publikationen.ub.uni-frankfurt.de
Hintergrund: Epilepsie bezeichnet eine Erkrankung, welche durch eine anhaltende
Prädisposition für Symptome, die im Zusammenhang mit einer ungewöhnlich starken oder …

[引用][C] GRADO EN BIOTECNOLOGÍA

ÍG Echevarría - 2023

Investigation of molecular mechanisms of cell death in human oligodendrocytes under metabolic stress

MG Forestieri Fernandes - 2024 - escholarship.mcgill.ca
Oligodendrocyte (OL) injury and loss is a feature of multiple sclerosis (MS) lesions and other
CNS disorders across the age spectrum. MS is known as an immune-mediated disease and …

Efecto del factor de crecimiento insulínico tipo II sobre el daño oxidativo-mitocondrial y neuronal inducido por MPP+ y corticosterona en neuronas dopaminérgicas en …

P Cabrera García - 2023 - riuma.uma.es
La Enfermedad de Parkinson (EP), es el trastorno de movimiento más frecuente, siendo la
segunda causa de enfermedad neurodegenerativa en todo el mundo. Se caracteriza por la …

[HTML][HTML] The identification of neuronal binding partners for human soluble amyloid precursor protein alpha

M Haycox - 2023 - escholar.manchester.ac.uk
Abstract †Dementia and Alzheimer’ s disease’ is the leading cause of death in the
UK, so new therapeutic options are of critical importance. One possible therapeutic avenue …

The role of α-synuclein in the gastrointestinal tract in Parkinson's disease

I Bunningen - 2023 - essay.utwente.nl
Parkinson's disease (PD) is the second most common neurodegenerative disease
worldwide (Dorsey et al., 2018). The past decays a wealth of evidence has witnessed that …

Age-dependent neuroprotective effect of an SK3 channel agonist on excitotoxity to dopaminergic neurons in organotypic culture

O Maldonado, A Jenkins, HM Belalcazar… - Plos one, 2020 - journals.plos.org
Background Small conductance, calcium-activated (SK3) potassium channels control the
intrinsic excitability of dopaminergic neurons (DN) in the midbrain and modulate their …

Experimental Models in Parkinson's Disease: Advantages and Disadvantages

Ö Altunlu, E Topatan, Z Al-yaqoobi, F Burul… - Ağrı Tıp Fakültesi … - dergipark.org.tr
Parkinson's disease is a complex neurodegenerative disease that affects millions of people
worldwide. The incidence and prevalence of Parkinson's disease, the second most common …

[PDF][PDF] IPSC-derived neurons and astrocytes: a novel patient-specific model to study the pre-degenerative molecular alteration in Parkinson's Disease

V Mutti - 2021 - iris.unibs.it
Untitled Page 1 Page 2 2 Page 3 3 Table of Contents: Abstract 5 Riassunto 8 1 Introduction 11
1.1 Parkinson’s Disease 11 1.1.1 Etiology 11 1.1.2 Pathophysiology 11 1.1.3 Therapy 14 1.2 …

Molecular mechanisms of GBA-linked PD

MM Halawani - 2021 - discovery.ucl.ac.uk
Objective: To investigate the effect of GBA heterozygote L444P (wt/L444P) mutation in
human dermal fibroblasts and mouse cortical neurons models (MCN) and find if …