Background Kinins are mediators of pain and inflammation. Their role in thermoregulation is,
however, unknown despite the fact the B1 receptor (B1R) was found implicated in …

Abstract Kinin B1 receptor (B1R) is virtually absent under physiological condition, yet it is
highly expressed in models of diabetes mellitus. This study aims at determining:(1) whether …

Background The endocannabinoid system modulates a wide variety of pain conditions.
Systemically administered AM404, an endocannabinoid reuptake inhibitor, exerts …

This research aimed at investigating the hypoglycemic effect of Zanthoxylum alkylamides
and whether TRPV1 receptor could participate in the glucose metabolism by using …

Epilepsy is one of the most common neurological diseases worldwide with a high
prevalence and unknown pathogenesis. Further, its control is challenging. It is generally …

缓激肽B1 受体(bradykinin 1 receptors, B1Rs) 是与Gq 蛋白相偶联的受体. 正常状态下, B1R
除了在神经系统中(如脊髓背角浅层和感觉神经节) 有少数表达外, 其他机体组织中几乎不存在 …

While brain kinin B1 receptor (B1R) is virtually absent in control rats, it contributes to
hypertension via a midbrain dopaminergic (DA) mechanism in spontaneously hypertensive …

The mechanisms of epidural-associated fever remain incompletely understood [1-3]. We
propose that action of local anesthetic on TPRV1. The transient receptor potential cation …

The transient receptor potential vanilloid 1 (TRPV1) is a nonselective cation channel with
high calcium permeability that has been studied extensively since its identification and …

Transkriptomanalysen unter Verwendung FACS-sortierter kortikaler Mikrogliazellen der
Maus haben ergeben, dass Transkripte des Ionenkanals Trpv2 im Vergleich zu anderen …