Collectively, cardiovascular diseases (CVD) are the leading cause of disability and death in
the United States (US), with risks for certain conditions differing between sexes. For …

Introduction: There is a growing need for the better understanding of the neurobiology that
underlies substance use disorder. The dopamine D3 receptor (DRD3) has received …

Plus de trois millions de morts sont attribués au tabagisme dans le monde par an, et l'usage
de tabac est en progression dans les pays en voie de développement. L'usage de tabac est …

Schizophrenia as currently conceptualized in the current version of the Diagnostic and
Statistical Manual of Mental Disorders (DSM-IV-TR) constitutes a broad and heterogeneous …

Although tobacco use is the leading cause of preventable death in the United States,
tobacco dependence remains an undertreated condition. Brief interactions with providers …

Cigarette smoking continues to be leading cause of preventable cause of death worldwide.
Cognitive modulation by nicotine seems to be a key factor in nicotine addiction. Several …

Maladaptive decision-making characterized by drug use despite the availability of many
alternative rewards is a key component of substance use disorders. However, the role of …

This paper discusses the harmful and fatal use of non-human animals in research. It argues
and demonstrates that such use can be scientifically invalid if the results are applied to …

Cytochrome P450 (CYP) enzymes play an important role in drug metabolism. While CYPs
are abundantly expressed in the liver, where CYP-mediated drug metabolism typically …