Ribonucleases (RNases) are mediators in most reactions of RNA metabolism. In recent
years, there has been a surge of new information about RNases and the roles they play in …

The continuous degradation and synthesis of prokaryotic mRNAs not only give rise to the
metabolic changes that are required as cells grow and divide but also rapid adaptation to …

In vitro, polynucleotide phosphorylase of Escherichia coli can both synthesize RNA by using
nucleotide diphosphates as precursors and exonucleolytically degrade RNA in the presence …

In Escherichia coli, the post‐transcriptional addition of poly (A) tails by poly (A) polymerase I
(PAP I, pcnB) plays a significant role in cellular RNA metabolism. However, many important …

When Apirion first proposed that mRNA decay in Escherichia coli involves a series of endo-
and exonucleolytic events (2), the general working assumption was that the turnover of …

One of the many important consequences that temperature down-shift has on cells is
stabilization of secondary structures of RNAs. This stabilization has wide-spread effects …

The problem of mRNA decay in E. coli has recently seen exciting progress, with the
discoveries that key degradation enzymes are associated together in a high molecular …

The Hfq protein, which shares sequence and structural homology with the Sm and Lsm
proteins, binds to various RNAs, primarily recognizing AU‐rich single‐stranded regions. In …

Mammalian mitochondria contain their own genome that encodes mRNAs for thirteen
essential subunits of the complexes performing oxidative phosporylation as well as the RNA …

The SmpB‐tmRNA‐mediated trans‐translation system has two well‐established activities:
rescuing ribosomes stalled on aberrant mRNAs and marking the associated protein …