Isolated methylmalonic acidaemia (MMA) and propionic acidaemia (PA) are rare inherited
metabolic diseases. Six years ago, a detailed evaluation of the available evidence on …

Objective The aim of this meta-analysis was to compare levels of health-related quality of life
(HRQOL) among children with and without chronic physical and/or sensory conditions …

Written by two leading experts in the field, this welcome third edition of Children in Difficulty:
A guide to understanding and helping discusses some of the most common, yet …

The sudden appearance and proliferation of coronavirus disease 2019 has forced societies
and governmental authorities across the world to confront the possibility of resource …

Background Long-term illness exposes children with chronic diseases to a high risk of
deterioration of physical and mental health. Developing an effective family resilience …

Evidence indicates that pediatric chronic health conditions (CHCs) often impair executive
functioning (EF) and impaired EF undermines pediatric CHC management. This …

Purpose To analyse: 1) the differences in health-related quality of life (HRQoL) between
typically developing (TD) children and children with developmental coordination disorder …

Background In recent decades, 95% of children with congenital heart disease (CHD) can
survive to adolescence and adulthood. However, adolescents with CHD are prone to poorer …

Objective Treatment of pediatric growth hormone deficiency (pGHD) with daily injection of
recombinant human growth hormone (somatropin) aims to increase height velocity and …

Background Despite the high prevalence of mental health difficulties in children and young
people with long-term health conditions (LTCs), these difficulties and experiences are often …