NK cell-based immunotherapy for malignant diseases
M Cheng, Y Chen, W Xiao, R Sun, Z Tian - Cellular & molecular …, 2013 - nature.com
Natural killer (NK) cells play critical roles in host immunity against cancer. In response,
cancers develop mechanisms to escape NK cell attack or induce defective NK cells. Current …
cancers develop mechanisms to escape NK cell attack or induce defective NK cells. Current …
Inflammatory cells in diffuse large B cell lymphoma
R Tamma, G Ranieri, G Ingravallo, T Annese… - Journal of Clinical …, 2020 - mdpi.com
Diffuse large B cell lymphoma (DLBCL), known as the most common non-Hodgkin
lymphoma (NHL) subtype, is characterized by high clinical and biological heterogeneity. The …
lymphoma (NHL) subtype, is characterized by high clinical and biological heterogeneity. The …
HIV-1-induced cytokines deplete homeostatic innate lymphoid cells and expand TCF7-dependent memory NK cells
Y Wang, L Lifshitz, K Gellatly, CL Vinton… - Nature …, 2020 - nature.com
Abstract Human immunodeficiency virus 1 (HIV-1) infection is associated with heightened
inflammation and excess risk of cardiovascular disease, cancer and other complications …
inflammation and excess risk of cardiovascular disease, cancer and other complications …
NK cells, displaying early activation, cytotoxicity and adhesion molecules, are associated with mild dengue disease
EL Azeredo, LM De Oliveira-Pinto… - Clinical & …, 2006 - academic.oup.com
During the innate immune response against infections, Natural Killer (NK) cells are as
important effector cells as are Cytotoxic T lymphocytes (CTL) generated after antigenic …
important effector cells as are Cytotoxic T lymphocytes (CTL) generated after antigenic …
The advances and challenges of NK cell-based cancer immunotherapy
S Kang, X Gao, L Zhang, E Yang, Y Li, L Yu - Current Oncology, 2021 - mdpi.com
Natural killer (NK) cells can be widely applied for cancer immunotherapy due to their ability
to lyse tumor targets without prior sensitization or human leukocyte antigens-matching …
to lyse tumor targets without prior sensitization or human leukocyte antigens-matching …
Targeting NK cells to enhance melanoma response to immunotherapies
Simple Summary NK cells are innate immune cells that form one of the initial responses to
infections and cancers. There have been increasing number of studies investigating the anti …
infections and cancers. There have been increasing number of studies investigating the anti …
Human small-intestinal epithelium contains functional natural killer lymphocytes
F León, E Roldán, L Sanchez, C Camarero, A Bootello… - Gastroenterology, 2003 - Elsevier
BACKGROUND & AIMS:: CD3− non-T lymphocytes constitute the second most abundant
lymphoid subset in the human small-bowel epithelium, and these CD3− intraepithelial …
lymphoid subset in the human small-bowel epithelium, and these CD3− intraepithelial …
Synthesis and surface expression of hyaluronan by dendritic cells and its potential role in antigen presentation
ME Mummert, D Mummert, D Edelbaum… - The Journal of …, 2002 - journals.aai.org
Hyaluronan (HA) is a large glycosaminoglycan consisting of repeating disaccharide units of
glucuronic acid and N-acetylglucosamine. HA is known to act as a filling material of …
glucuronic acid and N-acetylglucosamine. HA is known to act as a filling material of …
Signaling through CD38 induces NK cell activation
Human CD38 is a signal transduction molecule, and, concurrently, an ectoenzyme
catalyzing the synthesis and degradation of cyclic ADP-ribose (cADPR), a potent Ca2+ …
catalyzing the synthesis and degradation of cyclic ADP-ribose (cADPR), a potent Ca2+ …
CD38 triggers cytotoxic responses in activated human natural killer cells
G Sconocchia, JA Titus, A Mazzoni… - Blood, The Journal …, 1999 - ashpublications.org
Receptors used by natural killer (NK) cells to mediate natural cytotoxicity are poorly defined,
although it is now clear that a number of adhesion molecules can serve this function. CD38 …
although it is now clear that a number of adhesion molecules can serve this function. CD38 …