Machine learning applications in drug repurposing

F Yang, Q Zhang, X Ji, Y Zhang, W Li, S Peng… - Interdisciplinary Sciences …, 2022 - Springer
Abstract The coronavirus disease (COVID-19) has led to an rush to repurpose existing
drugs, although the underlying evidence base is of variable quality. Drug repurposing is a …

COVID-19 therapeutic potential of natural products

Z Low, R Lani, V Tiong, C Poh, S AbuBakar… - International Journal of …, 2023 - mdpi.com
Despite the fact that coronavirus disease 2019 (COVID-19) treatment and management are
now considerably regulated, severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

[HTML][HTML] Potential genes associated with COVID-19 and comorbidity

S Feng, F Song, W Guo, J Tan, X Zhang… - … journal of medical …, 2022 - ncbi.nlm.nih.gov
Hypertension, diabetes mellitus, and coronary artery disease are common comorbidities and
dangerous factors for infection and serious COVID-19. Polymorphisms in genes associated …

Composition, clinical efficiency, and mechanism of NHC-approved “Three Chinese Medicines and Three Chinese Recipes” for COVID-19 treatment

KY Xia, Z Zhao, T Shah, JY Wang… - Frontiers in …, 2022 - frontiersin.org
Traditional Chinese medicines (TCMs) have been regularly prescribed to treat and prevent
diseases for thousands of years in the eastern part of the Asian continent. Thus, when the …

Advances in pathogenesis, progression, potential targets and targeted therapeutic strategies in SARS-CoV-2-Induced COVID-19

H Zhou, WJ Ni, W Huang, Z Wang, M Cai… - Frontiers in …, 2022 - frontiersin.org
As the new year of 2020 approaches, an acute respiratory disease quietly caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), also known as coronavirus …

Traditional Chinese medicines against COVID-19: a global overview

CL Yao, WL Wei, JQ Zhang, QR Bi, JY Li… - World Journal of …, 2022 - journals.lww.com
Abstract Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory
syndrome coronavirus 2, continues to be a global concern. Traditional Chinese medicines …

[HTML][HTML] Therapeutic mechanisms and impact of traditional Chinese medicine on COVID-19 and other influenza diseases

T Shah, KY Xia, Z Shah, Z Baloch - Pharmacological Research-Modern …, 2022 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), first reported in Wuhan, China, has rapidly
spread worldwide. Traditional Chinese medicine (TCM) has been used to prevent and treat …

[HTML][HTML] New tale on LianHuaQingWen: IL6R/IL6/IL6ST complex is a potential target for COVID-19 treatment

Z Tianyu, C Xiaoli, W Yaru, Z Min, Y Fengli… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
LianHuaQingWen (LHQW) improves clinical symptoms and alleviates the severity of COVID-
19, but the mechanism is unclear. This study aimed to investigate the potential molecular …

Predicting for anti-(mutant) SARS-CoV-2 and anti-inflammation compounds of Lianhua Qingwen Capsules in treating COVID-19

L Hong, M He, S Li, J Zhao - Chinese Medicine, 2022 - Springer
Abstract Background Lianhua Qingwen Capsules (LHQW) is a traditional Chinese medicine
prescription commonly used to treat viral influenza in China. There has been sufficient …

Supercritical fluid coating of flavonoids on excipients enhances drug release and antioxidant activity

H He, Y Huang, X Zhang, Y Ouyang, P Pan… - International Journal of …, 2023 - Elsevier
Supercritical anti-solvent fluidized bed (SAS-FB) technology can be applied to reduce
particle size, prevent particle aggregation, and improve the dissolution and bioavailability of …