Lipoprotein (a) an elusive cardiovascular risk factor

L Berglund, R Ramakrishnan - Arteriosclerosis, thrombosis, and …, 2004 - Am Heart Assoc
Lipoprotein (a)[Lp (a)], is present only in humans, Old World nonhuman primates, and the
European hedgehog. Lp (a) has many properties in common with low-density lipoprotein …

Lipoprotein (a): a genetic marker for cardiovascular disease and target for emerging therapies

A Cesaro, A Schiavo, E Moscarella… - Journal of …, 2021 - journals.lww.com
Abstract Lipoprotein (a)[Lp (a)] is an established cardiovascular risk factor, and growing
evidence indicates its causal association with atherosclerotic disease because of the …

Apolipoprotein (a) gene accounts for greater than 90% of the variation in plasma lipoprotein (a) concentrations.

E Boerwinkle, CC Leffert, J Lin… - The Journal of …, 1992 - Am Soc Clin Investig
Plasma lipoprotein (a)[Lp (a)], a low density lipoprotein particle with an attached
apolipoprotein (a)[apo (a)], varies widely in concentration between individuals. These …

Effects of the apolipoprotein (a) size polymorphism on the lipoprotein (a) concentration in 7 ethnic groups

C Sandholzer, DM Hallman, N Saha, G Sigurdsson… - Human genetics, 1991 - Springer
Summary Apolipoprotein (a)[apo (a)] exhibits a genetic size polymorphism explaining about
40% of the variability in lipoprotein (a)[Lp (a)] concentration in Tyroleans. Lp (a) …

Lipoprotein metabolism during normal pregnancy

P Brizzi, G Tonolo, F Esposito, L Puddu… - American journal of …, 1999 - Elsevier
Objective: We sought to investigate the changes in circulating serum lipids and lipoproteins,
including lipoprotein (a), and low-density lipoprotein size in women during normal …

Effects of age, sex, and menopausal status on plasma lipoprotein (a) levels. The Framingham Offspring Study.

JL Jenner, JM Ordovas, S Lamon-Fava, MM Schaefer… - Circulation, 1993 - Am Heart Assoc
BACKGROUND Lipoprotein (a)[Lp (a)] is an atherogenic particle that structurally resembles
a low density lipoprotein (LDL) particle but contains a molecule of apolipoprotein (a) …

Lipoprotein (a) levels and risk of coronary heart disease in men: the Lipid Research Clinics Coronary Primary Prevention Trial

EJ Schaefer, S Lamon-Fava, JL Jenner, JR McNamara… - Jama, 1994 - jamanetwork.com
Objective.—To examine the relationship between elevated levels of lipoprotein (a)[Lp (a)]
and coronary heart disease (CHD) risk in a prospective study. Design.—Nested case-control …

Molecular basis of apolipoprotein (a) isoform size heterogeneity as revealed by pulsed-field gel electrophoresis.

C Lackner, E Boerwinkle, CC Leffert… - The Journal of …, 1991 - Am Soc Clin Investig
Lipoprotein (a)[Lp (a)] is a cholesterol-rich lipoprotein that is distinguished by its content of a
glycoprotein called apolipoprotein (a)[apo (a)]. Apo (a) varies in size among individuals …

The apolipoprotein (a) gene: a transcribed hypervariable locus controlling plasma lipoprotein (a) concentration

HG Kraft, S Köchl, HJ Menzel, C Sandholzer… - Human genetics, 1992 - Springer
Abstract Lipoprotein (a)[Lp (a)] is a quantitative trait in human plasma. Lp (a) consists of a
low-density lipoprotein and the plasminogen-related apolipoprotein (a)[apo (a)]. The apo (a) …

Nontraditional risk factors for coronary heart disease incidence among persons with diabetes: the Atherosclerosis Risk in Communities (ARIC) Study

I Saito, AR Folsom, FL Brancati, BB Duncan… - Annals of internal …, 2000 - acpjournals.org
Background: Major risk factors explain much of the excess risk for coronary heart disease
produced by diabetes, but nontraditional factors may also relate to incident coronary heart …