Stealth nanoparticles in oncology: Facing the PEG dilemma
S Zalba, TLM Ten Hagen, C Burgui… - Journal of Controlled …, 2022 - Elsevier
Nanoparticles (Nps) have revolutionized the landscape of many treatments, by modifying not
only pharmacokinetic properties of the encapsulated agent, but also providing a significant …
only pharmacokinetic properties of the encapsulated agent, but also providing a significant …
Surface modification strategies in translocating nano-vesicles across different barriers and the role of bio-vesicles in improving anticancer therapy
Nanovesicles and bio-vesicles (BVs) have emerged as promising tools to achieve targeted
cancer therapy due to their ability to overcome many of the key challenges currently being …
cancer therapy due to their ability to overcome many of the key challenges currently being …
The pro-tumorigenic host response to cancer therapies
Y Shaked - Nature Reviews Cancer, 2019 - nature.com
Resistance to cancer therapy remains a major challenge in clinical oncology. Although the
initial treatment phase is often successful, eventual resistance, characterized by tumour …
initial treatment phase is often successful, eventual resistance, characterized by tumour …
Cell membrane-camouflaged nanoparticles as drug carriers for cancer therapy
CH Xu, PJ Ye, YC Zhou, DX He, H Wei, CY Yu - Acta biomaterialia, 2020 - Elsevier
The translocation of natural cell membranes to the surface of synthetic nanoparticles, which
allows man-made vectors to share merits and functionalities created by nature, has been a …
allows man-made vectors to share merits and functionalities created by nature, has been a …
[HTML][HTML] The double edge sword of fibrosis in cancer
C Chandler, T Liu, R Buckanovich, LG Coffman - Translational Research, 2019 - Elsevier
Cancer-associated fibrosis is a critical component of the tumor microenvironment (TME)
which significantly impacts cancer behavior. However, there is significant controversy …
which significantly impacts cancer behavior. However, there is significant controversy …
Identifying the therapeutic significance of mesenchymal stem cells
The pleiotropic behavior of mesenchymal stem cells (MSCs) has gained global attention due
to their immense potential for immunosuppression and their therapeutic role in immune …
to their immense potential for immunosuppression and their therapeutic role in immune …
Mesenchymal stem cells in cancer progression and anticancer therapeutic resistance
X Xuan, C Tian, M Zhao, Y Sun, C Huang - Cancer cell international, 2021 - Springer
Increasing evidence indicates that the tumor microenvironment appears to play an
increasingly important role in cancer progression and therapeutic resistance. Several types …
increasingly important role in cancer progression and therapeutic resistance. Several types …
Tumour cell secretome in chemoresistance and tumour recurrence
Chemoresistance is a major factor driving tumour relapse and the high rates of cancer-
related deaths. Understanding how cancer cells overcome chemotherapy-induced cell …
related deaths. Understanding how cancer cells overcome chemotherapy-induced cell …
The multifaceted role of mesenchymal stem cells in cancer
Mesenchymal stem cells (MSCs) are multipotent stem cells derived from the mesoderm that
give rise to several mesenchymal lineages, including osteoblasts, adipocytes, chondrocytes …
give rise to several mesenchymal lineages, including osteoblasts, adipocytes, chondrocytes …
Stem cell–nanomedicine system as a theranostic bio-gadolinium agent for targeted neutron capture cancer therapy
The potential clinical application of gadolinium-neutron capture therapy (Gd-NCT) for
glioblastoma multiforme (GBM) treatment has been compromised by the fast clearance and …
glioblastoma multiforme (GBM) treatment has been compromised by the fast clearance and …