Characterizing regional drug delivery within the nasal airways

J Chen, WH Finlay, R Vehring… - Expert Opinion on Drug …, 2024 - Taylor & Francis
Introduction The nose has been receiving increased attention as a route for drug delivery. As
the site of deposition constitutes the first point of contact of the body with the drug …

Equilibrium solubility, solvent effect, and equation correlations of cyclosporine in twenty mono solvents and four binary mixtures

ES Ha, H Park, SK Lee, HT Kang, JS Jeong… - Journal of Molecular …, 2024 - Elsevier
In this study, the solid–liquid equilibrium solubility of cyclosporine in 20 pure solvents and
four binary mixtures at 298.15 K were determined using shake-flask technique. Solid-state …

[HTML][HTML] Polymyxin B sulfate inhalable microparticles with high-lectin-affinity sugar carriers for efficient treatment of biofilm-associated pulmonary infections

Y Zhou, J Huang, G Wang, Z Zhai, MU Ahmed, X Xia… - Science Bulletin, 2023 - Elsevier
Pulmonary infections caused by multidrug-resistant bacteria have become a significant
threat to human health. Bacterial biofilms exacerbate the persistence and recurrence of …

In vitro permeability study of nasal medicinal product for systemic action

IV Vlasenko - Problems of Biological Medical and …, 2024 - journals.eco-vector.com
For systemic medicinal products bioavailability is a fundamental characteristic that
determines their efficacy and onset of action. Biopharmaceutical parameters of nasal …