Interleukins (IL)-4 and-13 play a pivotal role in the pathobiology of type-2 asthma. Indeed, IL-
4 is crucially involved in Th2 cell differentiation, immunoglobulin (Ig) class switching and …

Food allergy affects more than 500 million people in the world, and its prevalence is
increasing at an alarming rate causing serious public health concerns; however, prevention …

Asthma and nasal polyposis often coexist and are frequently intertwined by tight pathogenic
links, mainly consisting of the cellular and molecular pathways underpinning type 2 airway …

The hygiene hypothesis has been popularized as an explanation for the rapid increase in
allergic disease observed over the past 50 years. Subsequent epidemiological studies have …

Background Breast cancer is a complex disease with a highly immunosuppressive tumor
microenvironment, and has limited clinical response to immune checkpoint blockade (ICB) …

Allergic rhinitis is a highly prevalent chronic inflammatory disorder of the nasal mucosa that
poses a significant burden on patients' health and quality of life. Current therapies for …

The term “allergic diseases” encompasses several common, IgE-mediated conditions that
range from being annoying to those that are life-threatening. Available treatments include …

Increasing attention has been paid to the potential impact of microplastics (MPs) pollution on
human health. MPs and phthalates coexist in the environment, however, the effects of …

Abstract Purpose of Review Increases in ambient levels of air pollutants have been linked to
lung inflammation and remodeling, processes that lead to the development and …

Epigallocatechin gallate (EGCG) is an active catechin in green tea and has multiple
biological functions, such as anti-inflammation, anti-cancer, and immune regulation. This …