Semaphorins are a large family of secreted and/or transmembrane proteins, originally
identified as proteins that function in axon guidance during neuronal development …

Introduction: Asthma is a condition of airflow limitation, common throughout the world, with
high mortality rates, especially as it still faces some obstacles in its management. As it …

Background Early microbial exposure is associate with protective allergic asthma. We have
previously demonstrated that Streptococcus pneumoniae aminopeptidase N (PepN), one of …

Placental growth factor (PlGF) is a glycosylated dimeric protein that is homologous to
vascular endothelial growth factor (VEGF). PlGF expression is upregulated in patients with …

Background Asthma is a heterogeneous disease characterized by airway inflammation and
remodeling, whose pathogenetic complexity was associated with abnormal responses of …

The silent information regulator sirtuin 1 (SIRT1) protein is an NAD+-dependent class-III
lysine deacetylase that serves as an important post-transcriptional modifier targeting lysine …

Asthma is a prevalent chronic respiratory disease, yet understanding its ecology and
pathogenesis remains a challenge. Trim27, a ubiquitination ligase belonging to the TRIM …

Recent evidence has increasingly underscored the importance of the neuro-immune axis in
mediating allergic airway diseases, such as allergic asthma and allergic rhinitis. The …

Background Asthma is a prevalent respiratory inflammatory disease. Abnormal apoptosis of
bronchial epithelial cells is one of the major factors in the progression of asthma. Peripheral …

Asthma is a common chronic respiratory disease, and its treatment is a core problem and
challenge in clinical practice. Glucocorticoids (GCs) are the first-line therapy for the …