Interleukin-33 (IL-33): A critical review of its biology and the mechanisms involved in its release as a potent extracellular cytokine
C Cayrol, JP Girard - Cytokine, 2022 - Elsevier
Abstract Interleukin-33 (IL-33), a member of the IL-1 family, is an alarmin cytokine with
crucial roles in tissue homeostasis and repair, type 2 immunity, allergic and non-allergic …
crucial roles in tissue homeostasis and repair, type 2 immunity, allergic and non-allergic …
[HTML][HTML] Cellular and functional heterogeneity of the airway epithelium
JD Davis, TP Wypych - Mucosal immunology, 2021 - Elsevier
The airway epithelium protects us from environmental insults, which we encounter with
every breath. Not only does it passively filter large particles, it also senses potential danger …
every breath. Not only does it passively filter large particles, it also senses potential danger …
After asthma: redefining airways diseases
Executive summary Asthma is responsible for considerable global morbidity and health-care
costs. Substantial progress was made against key outcomes such as hospital admissions …
costs. Substantial progress was made against key outcomes such as hospital admissions …
Interleukin‐33 (IL‐33): a nuclear cytokine from the IL‐1 family
C Cayrol, JP Girard - Immunological reviews, 2018 - Wiley Online Library
Summary Interleukin‐33 (IL‐33) is a tissue‐derived nuclear cytokine from the IL‐1 family
abundantly expressed in endothelial cells, epithelial cells and fibroblast‐like cells, both …
abundantly expressed in endothelial cells, epithelial cells and fibroblast‐like cells, both …
Epithelial cell–derived cytokines: more than just signaling the alarm
F Roan, K Obata-Ninomiya… - The Journal of clinical …, 2019 - Am Soc Clin Investig
The epithelial cell–derived cytokines thymic stromal lymphopoietin (TSLP), IL-33, and IL-25
are central regulators of type 2 immunity, which drives a broad array of allergic responses …
are central regulators of type 2 immunity, which drives a broad array of allergic responses …
Epithelial cell dysfunction, a major driver of asthma development
IH Heijink, VNS Kuchibhotla, MP Roffel, T Maes… - Allergy, 2020 - Wiley Online Library
Airway epithelial barrier dysfunction is frequently observed in asthma and may have
important implications. The physical barrier function of the airway epithelium is tightly …
important implications. The physical barrier function of the airway epithelium is tightly …
The life cycle of non-polio enteroviruses and how to target it
J Baggen, HJ Thibaut, JRPM Strating… - Nature Reviews …, 2018 - nature.com
The genus Enterovirus (EV) of the family Picornaviridae includes poliovirus,
coxsackieviruses, echoviruses, numbered enteroviruses and rhinoviruses. These diverse …
coxsackieviruses, echoviruses, numbered enteroviruses and rhinoviruses. These diverse …
Cellular and molecular mechanisms of allergic asthma
Asthma is a chronic disease of the airways, which affects more than 350 million people
worldwide. It is the most common chronic disease in children, affecting at least 30 million …
worldwide. It is the most common chronic disease in children, affecting at least 30 million …
Emerging functions of IL-33 in homeostasis and immunity
GK Dwyer, LM D'Cruz… - Annual review of …, 2022 - annualreviews.org
Our understanding of the functions of the IL-1 superfamily cytokine and damage-associated
molecular pattern IL-33 continues to evolve with our understanding of homeostasis and …
molecular pattern IL-33 continues to evolve with our understanding of homeostasis and …
Role of viral infections in the development and exacerbation of asthma in children
Viral infections are closely linked to wheezing illnesses in children of all ages. Respiratory
syncytial virus (RSV) is the main causative agent of bronchiolitis, whereas rhinovirus (RV) is …
syncytial virus (RSV) is the main causative agent of bronchiolitis, whereas rhinovirus (RV) is …