Diagnosis, prevalence, and clinical impact of sarcopenia in COPD: a systematic review and meta‐analysis

W Sepúlveda‐Loyola, C Osadnik, S Phu… - Journal of cachexia …, 2020 - Wiley Online Library
Sarcopenia prevalence and its clinical impact are reportedly variable in chronic obstructive
pulmonary disease (COPD) due partly to definition criteria. This review aimed to identify the …

Main pathogenic mechanisms and recent advances in COPD peripheral skeletal muscle wasting

P Henrot, I Dupin, P Schilfarth, P Esteves… - International Journal of …, 2023 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is a worldwide prevalent respiratory disease
mainly caused by tobacco smoke exposure. COPD is now considered as a systemic disease …

Towards personalized management of sarcopenia in COPD

SIJ van Bakel, HR Gosker, RC Langen… - … journal of chronic …, 2021 - Taylor & Francis
The awareness of the presence and consequences of sarcopenia has significantly
increased over the past decade. Sarcopenia is defined as gradual loss of muscle mass and …

Pathogenesis of sarcopenia in chronic obstructive pulmonary disease

K Ma, F Huang, R Qiao, L Miao - Frontiers in physiology, 2022 - frontiersin.org
Chronic obstructive pulmonary disease (COPD) is a common pulmonary disease
characterized by persistent respiratory symptoms and airflow obstruction. In addition to lung …

[HTML][HTML] Recent advances in understanding the role of FOXO3

RJ Stefanetti, S Voisin, A Russell, S Lamon - F1000Research, 2018 - ncbi.nlm.nih.gov
The forkhead box O3 (FOXO3, or FKHRL1) protein is a member of the FOXO subclass of
transcription factors. FOXO proteins were originally identified as regulators of insulin-related …

[HTML][HTML] Is inflammatory signaling involved in disease-related muscle wasting? Evidence from osteoarthritis, chronic obstructive pulmonary disease and type II …

S Dalle, K Koppo - Experimental gerontology, 2020 - Elsevier
Muscle loss is an important feature that occurs in multiple pathologies including
osteoarthritis (OA), chronic obstructive pulmonary disease (COPD) and type II diabetes …

Prevalence of sarcopenia in patients with COPD through different musculature measurements: an updated meta-analysis and meta-regression

J He, H Li, J Yao, Y Wang - Frontiers in Nutrition, 2023 - frontiersin.org
Aim Chronic obstructive pulmonary disease (COPD) patients vary widely in terms of the
prevalence of sarcopenia, which is partially attributed to differences in diagnostic criteria and …

Muscle changes during atrophy

A Dumitru, BM Radu, M Radu, SM Cretoiu - Muscle Atrophy, 2018 - Springer
Muscle atrophy typically is a direct effect of protein degradation induced by a diversity of
pathophysiologic states such as disuse, immobilization, denervation, aging, sepsis …

[HTML][HTML] FOXO3 on the road to longevity: lessons from SNPs and chromatin hubs

P Sanese, G Forte, V Disciglio, V Grossi… - Computational and …, 2019 - Elsevier
Health span is driven by a precise interplay between genes and the environment. Cell
response to environmental cues is mediated by signaling cascades and genetic variants that …

Deaccelerated myogenesis and autophagy in genetically induced pulmonary emphysema

J Balnis, LA Drake, DV Singer, CE Vincent… - American Journal of …, 2022 - atsjournals.org
Patients with chronic obstructive pulmonary disease (COPD)–pulmonary emphysema often
develop locomotor muscle dysfunction, which entails reduced muscle mass and force …