[HTML][HTML] Current status of research on exosomes in general, and for the diagnosis and treatment of kidney cancer in particular
W Mao, K Wang, Z Wu, B Xu, M Chen - Journal of Experimental & Clinical …, 2021 - Springer
Kidney cancer is a common urological tumour. Owing to its high prevalence and mortality
rate, it is the third most malignant tumour of the urinary system, followed by prostate and …
rate, it is the third most malignant tumour of the urinary system, followed by prostate and …
Ratiometric 3D DNA machine combined with machine learning algorithm for ultrasensitive and high-precision screening of early urinary diseases
N Wu, XY Zhang, J Xia, X Li, T Yang, JH Wang - Acs Nano, 2021 - ACS Publications
Urinary extracellular vesicles (uEVs) have received considerable attention as a potential
biomarker source for the diagnosis of urinary diseases. Present studies mainly focus on the …
biomarker source for the diagnosis of urinary diseases. Present studies mainly focus on the …
[HTML][HTML] Urinary extracellular vesicles as potential biomarkers for urologic cancers: An overview of current methods and advances
Simple Summary The diagnostic and monitoring techniques used for urologic cancers
comprise a group of invasive methodologies that still lack sensitivity and specificity …
comprise a group of invasive methodologies that still lack sensitivity and specificity …
[HTML][HTML] Mechanism of tumor‑derived extracellular vesicles in regulating renal cell carcinoma progression by the delivery of MALAT1
C Jin, L Shi, K Li, W Liu, Y Qiu, Y Zhao… - Oncology …, 2021 - spandidos-publications.com
Renal cell carcinoma (RCC) is a major healthcare burden globally. Tumor‑derived
extracellular vesicles (EVs) contribute to the formation of a pro‑metastatic microenvironment …
extracellular vesicles (EVs) contribute to the formation of a pro‑metastatic microenvironment …
[HTML][HTML] miR-224-5p contained in urinary extracellular vesicles regulates PD-L1 expression by inhibiting cyclin D1 in renal cell carcinoma cells
Z Qin, H Hu, W Sun, L Chen, S Jin, Q Xu, Y Liu, L Yu… - Cancers, 2021 - mdpi.com
Simple Summary The detailed effects of abundant microRNAs contained in extracellular
vesicles (EVs) on renal cell carcinoma (RCC) progression are still unclear. This study …
vesicles (EVs) on renal cell carcinoma (RCC) progression are still unclear. This study …
[HTML][HTML] Extracellular vesicles in renal cell carcinoma: Challenges and opportunities coexist
Y Lu, M Zhang, J Zhou, X Liu, L Wang, X Hu… - Frontiers in …, 2023 - frontiersin.org
Renal cell carcinoma (RCC) represents an extremely challenging disease in terms of both
diagnosis and treatment. It poses a significant threat to human health, with incidence rates …
diagnosis and treatment. It poses a significant threat to human health, with incidence rates …
Exosomal microRNA‐15a from ACHN cells aggravates clear cell renal cell carcinoma via the BTG2/PI3K/AKT axis
DY Li, FF Lin, GP Li, FC Zeng - The Kaohsiung journal of …, 2021 - Wiley Online Library
Accumulating studies have indicated that exosomal microRNAs (miRNAs/miRs) can mediate
clear cell renal cell carcinoma (ccRCC) at the early stage, but the mechanisms remain to be …
clear cell renal cell carcinoma (ccRCC) at the early stage, but the mechanisms remain to be …
[HTML][HTML] Advancements in the identification of EV derived mRNA biomarkers for liquid biopsy of clear cell renal cell carcinomas
MD Kuczler, RC Zieren, L Dong, TM de Reijke… - Urology, 2022 - Elsevier
Objective To propose EV-derived mRNA as a potential diagnostic biomarker detecting the
presence of clear cell renal cell carcinoma (ccRCC). There is currently no kidney cancer …
presence of clear cell renal cell carcinoma (ccRCC). There is currently no kidney cancer …
Recent advances in the molecular basis of chemotherapy resistance and potential application of epigenetic therapeutics in chemorefractory renal cell carcinoma
Among various types of cancers, kidney cancer is unique with respect to a low frequency of
mutations and a relatively higher level of chemotherapy resistance. Resistance to …
mutations and a relatively higher level of chemotherapy resistance. Resistance to …
[HTML][HTML] Extracellular vesicles in urological malignancies
MP Rimmer, CD Gregory, RT Mitchell - Biochimica et Biophysica Acta (BBA …, 2021 - Elsevier
Extracellular vesicles (EVs) are small lipid bound structures released from cells containing
bioactive cargoes. Both the type of cargo and amount loaded varies compared to that of the …
bioactive cargoes. Both the type of cargo and amount loaded varies compared to that of the …