Shape changing robots: bioinspiration, simulation, and physical realization

D Shah, B Yang, S Kriegman, M Levin… - Advanced …, 2021 - Wiley Online Library
One of the key differentiators between biological and artificial systems is the dynamic
plasticity of living tissues, enabling adaptation to different environmental conditions, tasks, or …

Synthetic morphology with agential materials

J Davies, M Levin - Nature Reviews Bioengineering, 2023 - nature.com
Bioengineering can address many important needs, from transformative biomedicine to
environmental remediation. In addition to practical applications, the construction of new …

A cellular platform for the development of synthetic living machines

D Blackiston, E Lederer, S Kriegman, S Garnier… - Science Robotics, 2021 - science.org
Robot swarms have, to date, been constructed from artificial materials. Motile biological
constructs have been created from muscle cells grown on precisely shaped scaffolds …

On having no head: cognition throughout biological systems

F Baluška, M Levin - Frontiers in psychology, 2016 - frontiersin.org
The central nervous system (CNS) underlies memory, perception, decision-making, and
behavior in numerous organisms. However, neural networks have no monopoly on the …

Knowing one's place: a free-energy approach to pattern regulation

K Friston, M Levin, B Sengupta… - Journal of the Royal …, 2015 - royalsocietypublishing.org
Understanding how organisms establish their form during embryogenesis and regeneration
represents a major knowledge gap in biological pattern formation. It has been recently …

The bioelectric code: An ancient computational medium for dynamic control of growth and form

M Levin, CJ Martyniuk - Biosystems, 2018 - Elsevier
What determines large-scale anatomy? DNA does not directly specify geometrical
arrangements of tissues and organs, and a process of encoding and decoding for …

Top-down models in biology: explanation and control of complex living systems above the molecular level

G Pezzulo, M Levin - Journal of The Royal Society …, 2016 - royalsocietypublishing.org
It is widely assumed in developmental biology and bioengineering that optimal
understanding and control of complex living systems follows from models of molecular …

Perspective: The promise of multi-cellular engineered living systems

RD Kamm, R Bashir, N Arora, RD Dar, MU Gillette… - APL …, 2018 - pubs.aip.org
Recent technological breakthroughs in our ability to derive and differentiate induced
pluripotent stem cells, organoid biology, organ-on-chip assays, and 3-D bioprinting have all …

[HTML][HTML] Future regenerative medicine developments and their therapeutic applications

AE Altyar, A El-Sayed, A Abdeen, M Piscopo… - Biomedicine & …, 2023 - Elsevier
Although the currently available pharmacological assays can cure most pathological
disorders, they have limited therapeutic value in relieving certain disorders like myocardial …

Mechanisms of urodele limb regeneration

DL Stocum - Regeneration, 2017 - Wiley Online Library
This review explores the historical and current state of our knowledge about urodele limb
regeneration. Topics discussed are (1) blastema formation by the proteolytic histolysis of …