Adult-onset Still's disease: clinical aspects and therapeutic approach

S Tomaras, CC Goetzke, T Kallinich, E Feist - Journal of clinical medicine, 2021 - mdpi.com
Adult-onset Still's disease (AoSD) is a rare systemic autoinflammatory disease characterized
by arthritis, spiking fever, skin rash and elevated ferritin levels. The reason behind the …

Adult-Onset Still's Disease—A Complex Disease, a Challenging Treatment

LA Macovei, A Burlui, I Bratoiu, C Rezus… - International Journal of …, 2022 - mdpi.com
Adult-onset Still's disease (AOSD) is a systemic inflammatory disorder with an unknown
cause characterized by high-spiking fever, lymphadenopathy, hepatosplenomegaly …

Ferritin triggers neutrophil extracellular trap-mediated cytokine storm through Msr1 contributing to adult-onset Still's disease pathogenesis

J Jia, M Wang, J Meng, Y Ma, Y Wang, N Miao… - Nature …, 2022 - nature.com
Hyperferritinemic syndrome, an overwhelming inflammatory condition, is characterized by
high ferritin levels, systemic inflammation and multi-organ dysfunction, but the pathogenic …

Systemic immune-inflammation index combined with ferritin can serve as a reliable assessment score for adult-onset Still's disease

JW Kim, JY Jung, CH Suh, HA Kim - Clinical Rheumatology, 2021 - Springer
Objective The diagnosis of adult-onset Still's disease (AOSD) is based on nonspecific
symptoms and laboratory data, and several infectious, autoimmune, and malignant diseases …

Neutrophil extracellular trap-induced intermediate monocytes trigger macrophage activation syndrome in adult-onset Still's disease

J Jia, M Wang, Y Ma, J Meng, D Zhu, X Chen, H Shi… - BMC medicine, 2023 - Springer
Abstract Background Adult-onset Still's disease (AOSD) is a systemic autoinflammatory
disease characterized by innate immune system activation, with a high risk for macrophage …

[HTML][HTML] Enhanced type I interferon signature induces neutrophil extracellular traps enriched in mitochondrial DNA in adult-onset Still's disease

Y Ma, M Wang, J Jia, J Meng, J Teng, D Zhu, H Shi… - Journal of …, 2022 - Elsevier
Adult-onset Still's disease (AOSD) is a rare but clinically well-known auto-inflammatory
disorder. Cytokine storm, the hallmark of AOSD, is mediated by neutrophil hyperactivation …

Urinary proteomics identifying novel biomarkers for the diagnosis of adult-onset Still's disease

Y Sun, F Wang, Z Zhou, J Teng, Y Su, H Chi… - Frontiers in …, 2020 - frontiersin.org
Adult-onset Still's disease (AOSD) is a systemic, multigenic autoinflammatory disease, and
the diagnosis of AOSD must rule out neoplasms, infections, and other autoimmune …

Circulating neutrophil extracellular traps signature for identifying organ involvement and response to glucocorticoid in adult-onset still's disease: a machine learning …

J Jia, M Wang, Y Ma, J Teng, H Shi, H Liu… - Frontiers in …, 2020 - frontiersin.org
Adult-onset Still's disease (AOSD) is an autoinflammatory disease with multisystem
involvement. Early identification of patients with severe complications and those refractory to …

Association of the Leukocyte Immunoglobulin‐like Receptor A3 Gene With Neutrophil Activation and Disease Susceptibility in Adult‐Onset Still's Disease

M Wang, M Liu, J Jia, H Shi, J Teng, H Liu… - Arthritis & …, 2021 - Wiley Online Library
Objective Adult‐onset Still's disease (AOSD) is a severe autoinflammatory disease.
Neutrophil activation with enhanced neutrophil extracellular trap (NET) formation is involved …

Proposal of a new diagnostic algorithm for adult-onset Still's disease

K Daghor-Abbaci, N Ait Hamadouche… - Clinical …, 2023 - Springer
Objective This study was performed to develop a new diagnostic algorithm for adult-onset
Still's disease (AOSD). Methods We conducted a multicenter prospective nationwide case …