Immunotherapy and liver transplantation: A narrative review of basic and clinical data

CH Wassmer, S El Hajji, X Papazarkadas… - Cancers, 2023 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) represents one of the main indications
for liver transplantation. Over recent years, immune checkpoint inhibitor (ICI) therapy has …

Transplant oncology: An emerging discipline of cancer treatment

M Abdelrahim, A Esmail, A Abudayyeh, N Murakami… - Cancers, 2023 - mdpi.com
Simple Summary Transplant oncology is an evolving treatment ideal for patients suffering
from various cancers with poor prognoses. The concept essentially is the complete removal …

Case Report: Successful liver transplantation after achieving complete clinical remission of advanced HCC with Atezolizumab plus Bevacizumab combination therapy

Y Chouik, D Erard, H Demian, T Schulz… - Frontiers in …, 2023 - frontiersin.org
Background Atezolizumab plus Bevacizumab combination therapy has recently emerged as
the new standard of care for unresectable HCC. Significant tumor burden reduction can be …

Immunotherapy use prior to liver transplant in patients with hepatocellular carcinoma

SM Woo, AV Kimchy, LM Sequeira, CS Dorris, AR He… - Current oncology, 2022 - mdpi.com
Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related mortality
worldwide, and its incidence has increased rapidly in the United States over the past two …

Newest therapies for cholangiocarcinoma: an updated overview of approved treatments with transplant oncology vision

Y Zhang, A Esmail, V Mazzaferro, M Abdelrahim - Cancers, 2022 - mdpi.com
Simple Summary Cholangiocarcinoma is a relatively rare but deadly disease with
traditionally limited treatment options. The disease can be categorized by anatomic location …

[HTML][HTML] When immunotherapy meets liver transplantation for hepatocellular carcinoma: a bumpy but promising road

Y Gu, S Xu, Z Wang, J Yang, S Zheng… - Chinese Journal of …, 2023 - ncbi.nlm.nih.gov
Liver transplantation (LT) is a highly curative therapy for patients with hepatocellular
carcinoma (HCC). However, due to the shortage of donor livers and rapid progression of …

Hepatocellular carcinoma: The role of immunotherapy and transplantation in the era of transplant oncology

S Alghamdi, W Al-Hamoudi - Cancers, 2023 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is a common cause of cancer-related
deaths worldwide. During the early stages of the disease, HCC can be treated with surgery …

Immunotherapy Plus Locoregional Therapy Leading to Curative-Intent Hepatectomy in HCC: Proof of Concept Producing Durable Survival Benefits Detectable with …

R Raj, CJ Wehrle, N Aykun, H Stitzel, WW Ma… - Cancers, 2023 - mdpi.com
Simple Summary Immunotherapy is emerging as an improved systemic treatment for select
patients with advanced unresectable hepatocellular carcinoma. An objective response is …

[HTML][HTML] Transplant oncology–Current indications and strategies to advance the field

FJ Krendl, R Bellotti, G Sapisochin, B Schaefer, H Tilg… - JHEP Reports, 2023 - Elsevier
Liver transplantation (LT) was originally described by Starzl as a promising strategy to treat
primary malignancies of the liver. Confronted with high recurrence rates and the missing …

Immune checkpoint inhibitors for solid tumors in the adjuvant setting: current progress, future directions, and role in transplant oncology

K Abboud, G Umoru, A Esmail, A Abudayyeh… - Cancers, 2023 - mdpi.com
Simple Summary Immune checkpoint inhibitors (ICIs) are being increasingly used after
primary treatment of early-stage tumors to treat any residual disease and prevent …