Exploring antimalarial potential: Conjugating organometallic moieties with organic fragments for enhanced efficacy

NAZ Norazmi, NH Mukhtar, L Ravindar, AS Saaidin… - Bioorganic …, 2024 - Elsevier
In the search for novel ligands with efficacy against various diseases, particularly parasitic
diseases, molecular hybridization of organometallic units into biologically active scaffolds …

A survey of isatin hybrids and their biological properties

VA Shu, DB Eni, F Ntie-Kang - Molecular Diversity, 2024 - Springer
The emergence of diverse infections worldwide, which is a serious global threat to human
existence, necessitates the urgent development of novel therapeutic candidates that can …

One-Pot Synthesis of 4-Chloroquinolines via Bis(trichloromethyl) Carbonate and Triphenylphosphine Oxide-Mediated Cascade Reactions of N-Aryl Enaminones

W Wang, D Feng, P Zhang, P Huang… - The Journal of Organic …, 2024 - ACS Publications
A novel method for synthesizing substituted 4-chloroquinolines has been devised, utilizing a
cascade reaction of N-aryl enaminones promoted by bis (trichloromethyl) carbonate (BTC) …

Lewis acid-mediated modular route to the synthesis of 3-substituted quinolines from 2-aminobenzyl alcohols and enamine (one) s

A Ghosh, S Upadhyay, DJ Dahatonde, R Kant… - New Journal of …, 2024 - pubs.rsc.org
A Lewis acid-mediated synthesis of 3-substituted quinolines from readily available 2-
aminobenzyl alcohols and N, N′-dimethylenamine (one) s is reported. The Friedlander …

Palladium-Catalyzed Domino Heteroarylation of Thioamides: A Simple Route to Benzothieno [2, 3-b] quinolones

M Janni, A Thirupathi, SV Subramaniam… - …, 2024 - thieme-connect.com
Domino reactions are essential for advancing organic synthesis. This study introduces novel
thioamide-based precursors for a palladium-catalyzed selective domino heteroarylation …

Three-Step Synthesis of N-(7-chloro-4-morpholinoquinolin-2-yl)benzamide from 4,7-Dichloroquinoline

DF Aparicio Acevedo, MC Ortiz Villamizar… - Molbank, 2024 - mdpi.com
The quinoline derivative, N-(7-chloro-4-morpholinoquinolin-2-yl) benzamide, was
synthesized in a conventional three-step procedure from 4, 7-dichloroquinoline using a N …

Three-Step Synthesis of N-(7-chloro-4-morpholinoquinolin-2-yl) benzamide from 4, 7-Dichloroquinoline

DFA Acevedo, MCO Villamizar, VV Kouznetsov - 2024 - preprints.org
Abstract The quinoline derivative, N-(7-chloro-4-morpholinoquinolin-2-yl) benzamide, was
synthesized in a conventional three-step procedure from 4, 7-dichloroquinoline using N …